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ProteomicsProteomic and Acetylome Alterations in Obesity-related Osteoarthritic Mouse Cartilage
Male mice aged 4 weeks were housed under controlled conditions and assigned to either a normal diet or a high-fat diet for 16 weeks to establish an obesity model. At 12 weeks, osteoarthritis was induced using the destabilization of the medial meniscus procedure under anesthesia, while sham-operated ...
ORGANISM(S): Mus Musculus 
2025-04-08 | PXD062707 |
ProteomicsReconstitution of Pluripotency from Mouse Fibroblast through Sall4 Overexpression
We report that SALL4 alone, under an optimized reprogramming medium iCD4, is capable of reprogramming mouse fibroblasts into iPSCs. To identify SALL4-direct-interacting proteins, we performed immunoprecipitation followed by mass spectrometry (IP-MS) using MEFs overexpressing WT-SALL4 or SALL4 mutan...
ORGANISM(S): Mus Musculus 
2024-11-05 | PXD057516 |
ProteomicsTargeting tRNA-dependent tyrosine usage unveils a metabolic vulnerability in hepatocellular carcinoma
proteomics and metabolomics analysis of HCC cells cultured in tyrosine deprived medium
ORGANISM(S): Homo Sapiens 
2025-12-30 | PXD072551 |
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