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TranscriptomicsCharacterizing a model human gut microbiota composed of members of its two dominant bacterial phyla
The adult human gut microbial community is typically dominated by two bacterial phyla (divisions), the Firmicutes and the Bacteroidetes. Little is known about the factors that govern the interactions between their members. Here we examine the niches of representatives of both phyla in vivo. Finishe...
ORGANISM(S): Bacteroides thetaiotaomicron 
2010-05-22 | E-GEOD-14737 | biostudies-arrayexpress
TranscriptomicsSaturated fat stimulates obesity and hepatic steatosis and affects gut microbiota composition by an enhanced overflow of dietary fat to the distal intestine
We studied the effect of dietary fat type, varying in polyunsaturated/saturated fatty acid ratio's (P/S) on development of metabolic syndrome. C57Bl/6J mice were fed purified high-fat diets (45E% fat) containing palm oil (HF-PO; P/S 0.4), olive oil (HF-OO; P/S 1.1) or safflower oil (HF-SO; P/S 7.8) ...
ORGANISM(S): Mus musculus 
2012-06-17 | E-GEOD-18586 | biostudies-arrayexpress
TranscriptomicsTranscriptional profile of B. theta and E. rectale growing in the cecum of mice fed different diets
The adult human gut microbial community is typically dominated by two bacterial phyla (divisions), the Firmicutes and the Bacteroidetes. Little is known about the factors that govern the interactions between their members. Here we examine the niches of representatives of both phyla in vivo. Finishe...
ORGANISM(S): Eubacterium rectale 
2010-05-22 | E-GEOD-14709 | biostudies-arrayexpress
TranscriptomicsMicrobial RNAseq analysis of cecal and fecal samples collected from mice colonized with the microbiota of human twins discordant for obesity
Microbial RNAseq analysis of cecal and fecal samples collected from mice colonized with the microbiota of human twins discordant for obesity. Samples were colleted at the time of sacrifice, or 15 days after colonization from mice gavaged with uncultured or cultured fecal microbiota from the lean twi...
ORGANISM(S): mouse gut metagenome 
2013-10-01 | E-GEOD-48861 | biostudies-arrayexpress
ProteomicsOuter membrane utilisomes mediate oligosaccharide uptake in gut Bacteroidetes
Bacteroidetes are abundant members of the human microbiota, and species occupying the distal gut are capable of utilising a myriad of diet- and host-derived glycans. Transport of glycans across the outer membrane (OM) of these bacteria is mediated by SusCD protein complexes. Additionally, cell surfa...
ORGANISM(S): Bacteroides thetaiotaomicron Bacteria 
2023-06-19 | PXD034863 | Pride
Outer membrane proteome Microbiota Glycan utilisation Gut bacteroidetes 
MetabolomicsMulti-Omics Unveils Strain-Specific Neuroactive Metabolite Production Linked to Inflammation Modulation by Bacteroides and Their Vesicles

18 Bacteroidetes isoaltes were analyzed for their neuroactive potentail using un-targeted and targeted metabolomics. The bacteria were grown to stationary phase, the supernatant was separated and purified using 0.22 um filter. The metabolome from the supernatant was extracted using standard Metha...

2025-08-12 | MTBLS10526 | MetaboLights
ProteomicsCharacterisation of the gut microbiota metaproteome in patients affected by the Williams Beuren syndrome
Analyses were performed on stool samples collected from 41 patients affected by Williams Beuren syndrome (Wills, WBSs) to evaluate their gut microbiota metaproteome signatures by LFQ and LCA approaches in comparison to 45 healthy subjects (controls, CTRs, CTRLs)
ORGANISM(S): Bacteria (ncbitaxon:2) Homo Sapiens (ncbitaxon:9606) 
2023-01-11 | MSV000091045 | MassIVE
ProteomicsMetaproteomics investigation on the gut microbiota of children affected by Autism Spectrum Disorder
Metaproteomics investigation of the Gut Microbiota in young subjects with Autism Spectrum Disorders and their relatives
ORGANISM(S): Bacteria (ncbitaxon:2) 
2020-04-06 | MSV000085232 | MassIVE
TranscriptomicsAltered interactions between the gut microbiome and colonic mucosa precede polyposis in APCMin/+ mice
Mutation of the adenomatous polyposis coli (APC gene), an early event in the adenoma-carcinoma sequence, is present in 70-80% of sporadic human colorectal adenomas and carcinomas. To test the hypothesis that mutation of the APC gene alters microbial interactions with host intestinal mucosa prior to...
ORGANISM(S): Mus musculus 
2015-08-24 | E-GEOD-67634 | biostudies-arrayexpress
MetabolomicsAlterations in the Gut Microbiota and Metabolomics of Seafarers after a Six-Month Sea Voyage

Maintaining the health of seafarers is a difficult task during long-term voyages. Little is known about the corresponding changes in the gut microbiome-host interaction. This study recruited 30 seafarers undertaking a 6-month voyage and analyzed their gut microbiota using 16S rRNA gene sequencing...

2022-09-29 | MTBLS5335 | MetaboLights
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