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ProteomicsRelating human gut metagenome and metaproteome
Gut microbiome research is rapidly moving towards the functional characterization of the microbiota by means of shotgun meta-omics. Here, we selected a cohort of healthy subjects from an indigenous and monitored Sardinian population to analyze their gut microbiota using both shotgun metagenomics and...
ORGANISM(S): human gut metagenome 
2017-07-19 | PXD005780 | Pride
Gut metagenome Gut metaproteome Metaproteomics 
ProteomicsCharacterisation of the gut microbiota metaproteome in patients affected by the Williams Beuren syndrome
Analyses were performed on stool samples collected from 41 patients affected by Williams Beuren syndrome (Wills, WBSs) to evaluate their gut microbiota metaproteome signatures by LFQ and LCA approaches in comparison to 45 healthy subjects (controls, CTRs, CTRLs)
ORGANISM(S): Bacteria (ncbitaxon:2) Homo Sapiens (ncbitaxon:9606) 
2023-01-11 | MSV000091045 | MassIVE
ProteomicsGut metaproteome of COVID-19 peadiatric patients
Stools from paediatric patients with COVID-19 were compared with age- and gender-matched healthy subjects to understand the functional roles of the gut microbial community in etiopathogenetic mechanisms of the disease trying to unveil new therapeutic targets.
ORGANISM(S): Bacteria (ncbitaxon:2) Homo Sapiens (ncbitaxon:9606) 
2023-08-11 | MSV000092639 | MassIVE
MetabolomicsConsistency across multi-omics layers in a drug-perturbed gut microbial community
Multi-omics analyses are increasingly employed in microbiome studies to obtain a holistic view of molecular changes occurring within microbial communities exposed to different conditions. However, it is not always clear to what extent each omics data type contributes to our understanding of the comm...
2022-12-08 | MTBLS3129 | MetaboLights
ProteomicsIntegrated metagenomics/metaproteomics reveals human host-microbiota signatures of Crohn's disease
Human gut metaproteome of select healthy and disease cohort.
ORGANISM(S): Human Gut Metaproteome 
2014-11-24 | MSV000078958 | MassIVE
Genomicsbeetle metagenome and metaproteome
beetle metagenome and metaproteome
PRJNA510434 | ENA
ProteomicsMouse gut metaproteome - MetaPro-IQ: a universal metaproteomic approach to studying human and mouse gut microbiota
The mouse stool samples were collected from different diets fed mice and bacterial cells were harvest for metaproteomic analysis for understanding the role ofdiet on gut microbiota.
ORGANISM(S): mouse gut metagenome 
2016-07-05 | PXD003527 | Pride
Mouse Gut microbiota Metaproteomics Lc-ms/ms 
ProteomicsFecal metaproteomics reveals reduced gut inflammation and changed microbial metabolism following lifestyle-induced weight loss
Aims Gut microbiota-mediated inflammation promotes obesity-associated low-grade inflammation, which represents a hallmark of the metabolic syndrome (MetS). Lifestyle-induced weight loss (WL) is regarded as an efficient therapy to reverse MetS and to prevent disease progression. The objective of this...
ORGANISM(S): human gut metagenome 
2021-04-19 | PXD020902 | Pride
Metaproteomics Obesity Metabolic syndrome Microbiome Gut inflammation Weight loss 
ProteomicsSequence database choice significantly affects taxonomic and functional metaproteomic results in gut microbiota studies
Elucidating the role of gut microbiota in physiological and pathological processes has recently emerged as a key research aim in life sciences. In this respect, metaproteomics (the study of the whole protein complement of a microbial community) can provide a unique contribution by revealing which fu...
ORGANISM(S): human gut metagenome 
2016-10-10 | PXD004039 | Pride
Metagenomics Bioinformatics Gut microbiota Metaproteomics 
ProteomicsMetaproteomics reveals persistent and phylum-redundant metabolic functional stability in adult human gut microbiomes despite temporal variations in microbial taxa, genomes, and proteomes
Longitudinal metaproteomics data set looking at the gut microbiome metaproteomes of fivepost-surgery Crohn's Disease patients for five time points over the course of a year.
ORGANISM(S): Human Microbiome 
2018-08-16 | MSV000082823 | MassIVE
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