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GenomicsThe Oral–Gut–Joint Axis in Osteoarthritis: A Multiomics Case‒Control Study
The Oral–Gut–Joint Axis in Osteoarthritis: A Multiomics Case‒Control Study
PRJNA1468542 | ENA
TranscriptomicsThe Oral–Gut–Joint Axis in Osteoarthritis: A Multiomics Case‒Control Study
Background: Osteoarthritis (OA) is a globally prevalent degenerative joint disorder that imposes significant socioeconomic burdens. While traditionally viewed as a localized “wear-and-tear” disease, emerging evidence supports a systemic pathogenesis involving the gut-joint axis. The oral-gut-joint p...
ORGANISM(S): Homo sapiens 
2026-05-27 | GSE331536 | GEO
ProteomicsProteomic Profiling of Inflammatory versus Noninflammatory Cartilage Regions in Knee Osteoarthritis Patients
This study performed data-independent acquisition (DIA)-based quantitative proteomic analysis on paired cartilage samples from inflammatory and noninflammatory regions of knee osteoarthritis (OA) patients. The objective was to characterize the proteomic alterations associated with cartilage inflamma...
ORGANISM(S): Homo Sapiens 
PXD078593 |
UnknownThe gut-joint axis mediates the TNF-induced RA process and PBMT therapeutic effects through the metabolites of gut microbiota.
Not available
S-EPMC10730145 | biostudies-literature
MetabolomicsStage-specific roles of microbial dysbiosis and metabolic disorders in rheumatoid arthritis

OBJECTIVE: Rheumatoid arthritis (RA) is a progressive disease including four stages, where gut microbiome is associated with pathogenesis. We aimed to investigate stage-specific roles of microbial dysbiosis and metabolic disorders in RA.

METHODS: We investi...

2023-01-31 | MTBLS5297 | MetaboLights
UnknownMulti-Omics Reveal the Dysregulated Gut-Joint Axis in Knee Synovitis: Data from Two Osteoarthritis Studies in China.
Not available
S-EPMC12866873 | biostudies-literature
UnknownGold nanoparticles exhibit anti-osteoarthritic effects via modulating interaction of the "microbiota-gut-joint" axis.
Not available
S-EPMC11000357 | biostudies-literature
UnknownNew bitongling regulates gut microbiota to predict angiogenesis in rheumatoid arthritis via the gut-joint axis: a deep neural network approach.
Not available
S-EPMC11830818 | biostudies-literature
UnknownMiya Improves Osteoarthritis Characteristics via the Gut-Muscle-Joint Axis According to Multi-Omics Analyses.
Not available
S-EPMC9163738 | biostudies-literature
UnknownStructure-Tailoring Cerium Nanozymes with Self-Cascade ROS Scavenging Catalysis Modulate the Microbiota-Gut-Joint Axis for Rheumatoid Arthritis Therapy.
Not available
S-EPMC12713043 | biostudies-literature
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