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ProteomicsProteomic identification of an endogenous synaptic SUMOylome in the developing rat brain
Synapses are highly specialized structures that interconnect neurons to form functional networks dedicated to neuronal communication. During brain development, synapses undergo activity-dependent rearrangements leading to both structural and functional changes. Many molecular processes are involved ...
ORGANISM(S): Rattus norvegicus (Rat) 
2021-11-25 | PXD028804 | Pride
Post-translational modification Developping rat brain Synapse Sumo 
ProteomicsCombining affinity purification and mass spectrometry to define the network of the nuclear proteins interacting with the N-terminal region of FMRP
We identified a nuclear interactome of FMRP by combining subcellular fractionation of rat brains at the post-natal day 14 with pull down affinity purification and mass spectrometry analysis. By this approach, we have listed 55 candidate nuclear partners.
ORGANISM(S): Rattus norvegicus (Rat) 
2022-08-14 | PXD034157 | Pride
Nuclear protein network Mrna metabolism Proteomics Nuclear fractionation Fmrp 
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