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UnknownH2BK120ub and its reader RNF169 sequentially regulate replication fork remodeling and stability.
Not available
S-EPMC12623888 | biostudies-literature
ProteomicsAn optimized and robust workflow for quantifying the canonical histone ubiquitination marks H2AK119ub and H2BK120ub by LC-MS/MS
The eukaryotic genome is packaged around histone proteins, which are subject to a myriad of post-translational modifications. By controlling DNA accessibility and the recruitment of protein complexes that mediate chromatin-related processes, these modifications constitute a key mechanism of epigenet...
ORGANISM(S): Homo sapiens (Human) 
2024-10-16 | PXD052972 | Pride
Histone post-translational modifications H2ak119ub H2bk120ub Ubiquitination 
UnknownAtypical plant homeodomain of UBR7 functions as an H2BK120Ub ligase and breast tumor suppressor.
Not available
S-EPMC6438984 | biostudies-literature
UnknownOptimized and Robust Workflow for Quantifying the Canonical Histone Ubiquitination Marks H2AK119ub and H2BK120ub by LC-MS/MS.
Not available
S-EPMC11932154 | biostudies-literature
UnknownAn optimized and robust workflow for quantifying the canonical histone ubiquitination marks H2AK119ub and H2BK120ub by LC-MS/MS.
Not available
S-EPMC11195131 | biostudies-literature
UnknownH2BK120ub and its reader RNF169 sequentially regulate replication fork remodeling and stability
Not available
S-SCDT-10_1038-S44318-025-00602-1 | biostudies-other
TranscriptomicsThe chromatin-binding protein PHF6 functions as an E3 ubiquitin ligase of H2BK120 via H2BK12Ac recognition for activation of trophectodermal genes
Epigenetic regulation is important for establishing lineage-specific gene expression during early development. Although signaling pathways have been well-studied for regulation of trophectoderm reprogramming, epigenetic regulation of trophectodermal genes with histone modification dynamics have been...
ORGANISM(S): Mus musculus 
2020-07-13 | GSE144298 | GEO
UnknownUbiquitinated histone H2B as gatekeeper of the nucleosome acidic patch.
Not available
S-EPMC11381367 | biostudies-literature
UnknownFunctional crosstalk between histone H2B ubiquitylation and H2A modifications and variants.
Not available
S-EPMC5895630 | biostudies-literature
UnknownMechanistic basis for the opposing effects of H2A and H2B ubiquitination on nucleosome stability and dynamics.
Not available
S-EPMC12628893 | biostudies-literature
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