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Expression data of H838 KRAS mutation isogenic cell lines
To explore the distinct mechanism of KRAS G12V and G12D mutation. We used microarray to explore the distinct differences in gene expression profiles of H838 KRAS mutation isogenic cell lines
ORGANISM(S): Homo sapiens 
2020-05-21 | GSE119146 | GEO
Transcriptome sequencing of human lung cancer cell line NCI-H838 treated with LINC00472 overexpression
Numerous RNA-binding proteins involved in alternative polyadenylation are arginine methylation substrates. Therefore we aimed to study how alternative polyadenylation is impacted by preventing arginine methylation, and assess how conserved this phenotype is across a panel of cancer lines with differ...
ORGANISM(S): Homo sapiens 
The goal of this study was to examine transcriptional responses to the SMARCA2-selective degrader PRT3789, standard chemotherapies, and their combinations in SMARCA4-deficient NCI-H838 xenograft tumors. Six treatment groups were evaluated: (1) vehicle control, (2) PRT3789, (3) docetaxel, (4) nab-pac...
ORGANISM(S): Homo sapiens 
2025-09-12 | GSE307427 | GEO
RNA-seq analysis of SMARCA4-deficient NCI-H838 xenograft tumors treated with PRT3789, docetaxel, nab-paclitaxel, or combination regimens
Respones to treatment of H209 and H838 cell lines to treatment with the non-covalent inhibitor of TRXR1, DKFZ-608
Mindbomb1 is a Novel Negative Regulator of BMP Signaling (H838: MIB1 iKO)
Mindbomb1 is a Novel Negative Regulator of BMP Signaling (H838: MIB1 iKO, +BMP4, -/+ BMP inhibitor)
Recent studies have noted the tumor-stroma interaction as an integral part of tumor growth and spread as well as novel avenues for effective treatment. However, the details by which tumor and stroma cells communicate remain poorly understood. Here we show that the migration speed of the non-small-ce...
ORGANISM(S): Homo sapiens 
2020-08-20 | GSE42076 | GEO
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