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Ischemic heart disease continues to rank highly among cardiovascular diseases in the world. Myocardial reperfusion (R) is provided with an effective and rapid treatment, however it can lead to fatal results as well as ischemia (I). The goal of this study was to use proteomic analysis to assess the p...
ORGANISM(S): Rattus norvegicus (Rat) 
2024-07-25 | PXD047994 | Pride
The rat cardio-myoblast cell line H9C2 has emerged as an important tool for studying cardiac development and toxicology. We present here a rigorous proteomic analysis that for the first time studied changes of proteins during H9C2 differentiation into cardiomyocyte-like cells over time. Quantitative...
ORGANISM(S): Rattus norvegicus (Rat) 
2018-11-07 | PXD006115 | Pride
The human HEK293 / 293T and rat cardiomyoblast H9c2 cell lines are commonly employed for microRNA-mRNA interaction studies. Here, I provide microRNA sequencing data obtained from each of these lines to better document which microRNAs are endogenously expressed at high or low levels. Small RNA sequen...
ORGANISM(S): Rattus norvegicus 
H9c2 cells with or without lactate
H9c2 cell response after retinoic acid stimuli
H9c2 cells with or without lactate (1hr)
microRNA sequencing of HEK293 and H9c2 cells
Hypoxia as a crucial pathogenesis factor usually results in huge harmful effects on cardiac injury and dysfunction. In our previous study (PMID: 33294289), We observe a series of differential expressed genes between transcription and translation, which may be attributed to the hypoxia-specific bindi...
ORGANISM(S): Rattus norvegicus 
During culture, H9c2 cells acquire a myotubule phenotype where a critical component is the inclusion of retinoic acid (RA). The results from some authors on H9c2 suggested that thousands of genes respond to RA stimuli, while other authors report hundreds of genes responding to RA over different cell...
ORGANISM(S): Rattus norvegicus 
2022-12-22 | GSE221596 | GEO
Genome-wide maps in H9C2 cells with or without PAGln treatment (100 μM)
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