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The cerebral cortex plays an important role in cognitive function and specialized perception in mammals and its development requires highly specific spatio-temporal control of gene expression. The study identified stage- and region-specific markers throughout cerebral corticogenesis at various impor...
ORGANISM(S): Mus musculus 
Nonsense-mediated mRNA decay (NMD) surveillance pathways are best known to be involved in the degradation of mRNA with premature termination codons (PTCs). More recent studies demonstrate that the role of NMD pathways goes well beyond the degradation of PTC containing mRNA, into the regulation of ce...
ORGANISM(S): Homo sapiens 
Keratinocyte proliferation and differentiation is regulated via proteolytic networks. Dysregulation of proteases within these systems can cause hyperproliferative and inflammatory skin disorders. In healthy skin the metalloprotease meprin α is localized in the stratum basale, yet in wound healing ti...
ORGANISM(S): Mus musculus (Mouse) 
2026-02-03 | PXD063928 | Pride
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