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Collateral lethality occurs when loss of one paralog renders cancer cells dependent on the remaining paralog. Combining genome scale CRISPR/Cas9 screens coupled with RNA-sequencing in over 900 cancer cell lines, we found that cancers of nervous system lineage, including adult and pediatric gliomas a...
ORGANISM(S): Homo sapiens (Human) 
2022-09-06 | PXD030599 | Pride
We analyzed 29 Sialolith samples, employing classical Population Genetic principles (Hartl and Clark 1980 (1), Hahn 2018 (2)) and Systems Biology analysis (ed: by Rigoustsos and Stephanopoulos 2006 (3)) approaches to create specific algorithms designed for our research objectives. Using these method...
ORGANISM(S): Homo sapiens (Human) 
2020-04-16 | PXD012422 | Pride
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