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MetabolomicsNitisinone’s mosquitocidal properties hold promise for malaria control

Nitisinone’s mosquitocidal properties hold promise for malaria control

2025-06-16 | MTBLS11617 | MetaboLights
MetabolomicsRepurposing the orphan drug nitisinone to control the transmission of African trypanosomiasis
Tsetse transmit African trypanosomiasis, which is a disease fatal to both humans and animals. A vaccine to protect against this disease does not exist so transmission control relies on eliminating tsetse populations. Although neurotoxic insecticides are the gold standard for insect control, they neg...
2021-10-06 | MTBLS2166 | MetaboLights
GenomicsNational Eye Institute Glaucoma Human Genetics Collaboration (NEIGHBOR) Consortium Glaucoma Genome-Wide Association Study

This is a case-control study of primary open angle glaucoma (POAG). POAG is an intraocular pressure (IOP) related progressive optic neuropathy that ultimately leads to blindness. For this study we have formed a collaborative consortium contributing 2170 POAG cases and 2347 controls with a unified...

phs000238.v1.p1 | EGA
UnknownDNA copy number variants of known glaucoma genes in relation to primary open-angle glaucoma.
Not available
S-EPMC4271633 | biostudies-literature
UnknownGenome-wide analysis of central corneal thickness in primary open-angle glaucoma cases in the NEIGHBOR and GLAUGEN consortia.
Not available
S-EPMC3394688 | biostudies-literature
UnknownAssociation of a Primary Open-Angle Glaucoma Genetic Risk Score With Earlier Age at Diagnosis.
Not available
S-EPMC6707005 | biostudies-literature
UnknownCross-ancestry genome-wide association analysis of corneal thickness strengthens link between complex and Mendelian eye diseases.
Not available
S-EPMC5951816 | biostudies-literature
UnknownAssessing the Association of Mitochondrial Genetic Variation With Primary Open-Angle Glaucoma Using Gene-Set Analyses.
Not available
S-EPMC5040191 | biostudies-literature
UnknownMechanosensitive ion channel gene survey suggests potential roles in primary open angle glaucoma.
Not available
S-EPMC10517927 | biostudies-literature
UnknownA Common Variant in MIR182 Is Associated With Primary Open-Angle Glaucoma in the NEIGHBORHOOD Consortium.
Not available
S-EPMC4991020 | biostudies-literature
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