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TranscriptomicsInsulin-like Signaling Determines Survival During Stress via Post Transcriptional Mechanisms in C. elegans.
The insulin-like signaling (ILS) pathway regulates metabolism and is known to modulate adult lifespan in C. elegans. Altered stress responses and resistance to a wide range of stressors are also associated with changes in ILS and contribute to enhanced longevity. The transcription factors DAF-16 and...
ORGANISM(S): Caenorhabditis elegans 
2010-06-17 | E-GEOD-22383 | biostudies-arrayexpress
TranscriptomicsTranscriptional profiling of zebrafish embryos developmentally exposed to oxygenated PAHs 1,9-benz-10-anthrone and benzanthracene-7,12-dione
The purpose of this study was to identify transcripts differentially expressed in zebrafish embryos exposed to two oxygenated PAHs, 1,9-benz-10-anthrone and benzanthracene-7,12-dione, which cause abnormal development. We used RNA-seq (Illumina HiSeq) to identify mRNA profiles of whole zebrafish embr...
ORGANISM(S): Danio rerio 
2015-07-06 | E-GEOD-68666 | biostudies-arrayexpress
TranscriptomicsTranscriptional profiling of zebrafish embryos after 96 h exposure to two subsequent concentrations of 4-methyl-3-deoxy-1,9,12-trihydroxyestra-1,3,5(10)7-tetraene-6,17-dione (MDTETD) and 12β-trihydroxy-androsta-4,6-diene-3,17-dione (THADD)
The aim of this mRNA expression profiling experiment was to screen for ecotoxicogenomic fingerprints in zebrafish (Danio rerio) embryos as aquatic vertebrate non-target model exposed to sublethal concentrations of 4-methyl-3-deoxy-1,9,12-trihydroxyestra-1,3,5(10)7-tetraene-6,17-dione (MDTETD) and 12...
ORGANISM(S): Danio rerio 
2021-10-11 | E-MTAB-10922 | biostudies-arrayexpress
TranscriptomicsBaseline expression from transcriptional profiling of zebrafish developmental stages
Establish baseline expression transcriptional signatures for zebrafish developmental stages. Total RNA was extracted from single wild type zebrafish embryos at a series of different developmental stages. RNA from 12 embryos was pooled to generate a replicate.The RNA was DNase treated. Stranded RNAs...
ORGANISM(S): Danio rerio 
2016-06-12 | E-ERAD-475 | biostudies-arrayexpress
TranscriptomicsTranscriptional profiling of tfap2a;tfap2c loss of function in zebrafish single whole embryos at 15 somites post fertilisation
We have genetically ablated the neural crest by simultaneously knocking out tfap2a and tfap2c in developing zebrafish embryos. We have collected 10 single embryos at the 15 somites stage from all nine possible genotypic combinations which can be found when heterozygous parent carriers of tfap2a and ...
ORGANISM(S): Danio rerio 
2018-05-01 | E-MTAB-6106 | biostudies-arrayexpress
UnknownGradient-Boosting Classifiers Combining Vessel Density and Tissue Thickness Measurements for Classifying Early to Moderate Glaucoma.
Not available
S-EPMC7492367 | biostudies-literature
UnknownRelationship of Corneal Hysteresis and Anterior Lamina Cribrosa Displacement in Glaucoma.
Not available
S-EPMC7113091 | biostudies-literature
UnknownPerformance of Deep Learning Architectures and Transfer Learning for Detecting Glaucomatous Optic Neuropathy in Fundus Photographs.
Not available
S-EPMC6232132 | biostudies-literature
UnknownDeep Learning Approaches Predict Glaucomatous Visual Field Damage from OCT Optic Nerve Head En Face Images and Retinal Nerve Fiber Layer Thickness Maps.
Not available
S-EPMC8063221 | biostudies-literature
UnknownDeep Learning Image Analysis of Optical Coherence Tomography Angiography Measured Vessel Density Improves Classification of Healthy and Glaucoma Eyes.
Not available
S-EPMC10042115 | biostudies-literature
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