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ProteomicsQuantitative proteomic analysis of CKD urine samples
Urinary proteomics studies have primarily focused on identifying markers of chronic kidney disease (CKD) progression. Here, we aimed to specify CKD-related injury markers through proteomics analysis in urine of patients with CKD. Label-free quantitative proteomics analysis based on liquid chromatogr...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-06-15 | MSV000087635 | MassIVE
TranscriptomicsExpression profiles from HEK293 cells by overexpression of TRPM7 channel
The functional activity of TRPM7 is essential for cell viability and growth, and its expression is up-regulated in certain pathological conditions. In order to assess the effects of TRPM7 activity on cellular gene expression, inducible HEK293 cell-lines harboring the wild-type mouse TRPM7 and a muta...
ORGANISM(S): Homo sapiens 
2011-07-22 | E-GEOD-23102 | biostudies-arrayexpress
ProteomicsAnti-proteolytic regulation of KRAS by USP9X/NDRG3 in KRAS-driven cancer development
Cancers with activating mutations of KRAS show a high prevalence and poor prognosis but remain intractable, requiring innovative strategies to overcome the poor targetability of KRAS. Here, we report that KRAS expression was post-translationally up-regulated through the deubiquitination of KRAS prot...
ORGANISM(S): Homo sapiens (Human) 
2025-05-06 | PXD051954 | Pride
Kras protein deubiquitination  ndrg3  usp9x  pancreatic cancer 
ProteomicsDifferential Protein Expression and Metabolite Profiling in Glaucoma: Insights from a Multi-Omics Analysis
Glaucoma is a group of diseases characterized by progressive optic nerve damage leading to irreversible visual field loss, often associated with elevated intraocular pressure (IOP). However, the specific underlying factors or molecular mechanisms distinguishing various glaucoma subtypes are still no...
ORGANISM(S): Homo sapiens (Human) 
2024-04-11 | PXD046219 | Pride
Proteomics Multi-omics Metabolomics Pseudoexfoliation Primary open-angle glaucoma Extracellular matrix 
ProteomicsAnti-proteolytic regulation of KRAS by USP9X/NDRG3 in KRAS-driven cancer development
Cancers with activating mutations of KRAS show a high prevalence and poor prognosis but remain intractable, requiring innovative strategies to overcome the poor targetability of KRAS. Here, we report that KRAS expression was post-translationally up-regulated through the deubiquitination of KRAS prot...
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD052379 | Pride
Kras protein deubiquitination  ndrg3  usp9x  pancreatic cancer 
TranscriptomicsAnti-cancer drug sensitive DNA methylation marker research
Genome wide DNA methylation profiling of normal and colon cancer and assosiation study between anti-cancer drug respond group and non-respond group. The Illumina Infinium 27k Human DNA methylation Beadchip v1.2 was used to obtain DNA methylation profiles across approximately 27,000 CpGs in 118 pair...
ORGANISM(S): Homo sapiens 
2011-12-31 | E-GEOD-27130 | biostudies-arrayexpress
UnknownStructure analysis of a new psychrophilic marine protease.
Not available
S-EPMC3223159 | biostudies-literature
UnknownTRAIP/RNF206 is required for recruitment of RAP80 to sites of DNA damage.
Not available
S-EPMC4735692 | biostudies-literature
TranscriptomicsDNA methylation represents one of the key regulator that transcriptional control of highly expressed genes in gastric cancer.
We used microarray approach to establish demethylated specific genes profiles in early gastric cancer. We analyzed 11 gastric cancer cell lines and 32 pairs of gastric cancer and normal samples to discover methylation signatures specific to gastric cancer cells.
ORGANISM(S): Homo sapiens 
2011-05-31 | E-GEOD-25869 | biostudies-arrayexpress
UnknownSLC6A20 transporter: a novel regulator of brain glycine homeostasis and NMDAR function
Not available
S-SCDT-EMM-2020-12632 | biostudies-other
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