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The function of a gene is closely connected to its expression specificity across tissues and cell types. RNA-Seq is a powerful quantitative tool to explore genome wide expression. The aim of the present study is to provide a comprehensive RNA-Seq dataset across the same 13 tissues for mouse and rat,...
ORGANISM(S): Rattus norvegicus 
Biomarker assessments based on kidney tissue evaluations show a direct correlation with renal fibrosis, but are limited by their invasive nature. Consequently, there is a growing interest in noninvasive biomarkers based on urine and blood samples. However, the utility of urine samples is limited by ...
ORGANISM(S): Homo sapiens (Human) 
2025-05-06 | PXD043922 | Pride
Breast cancer accounts for roughly 30% of all cancers in women worldwide, has a 15% death rate, and incidence rates are increasing at a rate of about 0.5% per year. Breast cancer comprises a heterogeneous group of tumor subtypes, whether defined by the histopathology of the primary tumor, the expres...
ORGANISM(S): Homo sapiens (Human) 
2022-04-04 | PXD030881 | Pride
The direct inflammatory action of proprotein convertase subtilisin/kexin type 9 (PCSK9) is examined in vitro in monocytes and endothelial cells, as well as via an in vivo atherosclerosis animal model. PCSK9 exacerbates atherosclerosis in low-density lipoprotein receptor (LDLR)-/- mice, indicating an...
ORGANISM(S): Homo sapiens (Human) 
2024-06-16 | PXD047058 | Pride
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