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Cap1p, a transcription factor of the basic region-leucine zipper family, regulates oxidative stress response (OSR) in Candida albicans. Alteration of its C-terminal cysteine-rich domain (CRD) results in Cap1p nuclear retention and transcriptional activation. To better understand the function of Ca...
ORGANISM(S): Candida albicans 
Cap1p, a transcription factor of the basic region-leucine zipper family, controls the oxidative stress response in Candida albicans. It was shown that alteration of the C-terminal cysteine-rich domain (CRD) of Cap1p results in nuclear retention and constitutive transcriptional activation. To further...
ORGANISM(S): Candida albicans 
Serum response factor (SRF) is a ubiquitously expressed transcription factor that is essential for brain development and function. SRF activity is controlled by two competing classes of coactivators, myocardin-related transcription factors (MRTF) and ternary complex factors, which introduce specific...
ORGANISM(S): Mus musculus (Mouse) 
2025-01-14 | PXD051147 | Pride
Constitutive overexpression of the Mdr1 efflux pump is an important mechanism of acquired drug resistance in the yeast Candida albicans. The zinc cluster transcription factor Mrr1 is a central regulator of MDR1 expression, but other transcription factors have also been implicated in MDR1 regulation....
ORGANISM(S): Candida albicans 
Mouse lung injury-repair induces Ntrk2-tk in CAP1 endothelial cells (scATAC-Seq)
Mouse lung injury-repair induces Ntrk2-tk in CAP1 endothelial cells (scRNA-Seq)
The CAP1 represses MRTF-SRF–dependent gene expression in the mouse cerebral cortex by an actin-dependent mechanism
Serum response factor (SRF) is a ubiquitously expressed transcription factor that is essential for brain development and function. SRF activity is controlled by two competing classes of coactivators, myocardin-related transcription factors (MRTF) and ternary complex factors, which introduce specific...
ORGANISM(S): Mus musculus 
2024-03-22 | GSE262154 | GEO
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