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TranscriptomicsNon-alcoholic steatohepatitis causes selective CD4+ T cell loss and promotes hepatocarcinogenesis
Hepatocellular carcinoma (HCC) is the second most common cause of cancer related death. NAFLD affects a large proportion of the US population. Its incidence and prevalence are increasing to epidemic proportions around the world and is known to increase the risk of HCC. We studied how intrahepatic li...
ORGANISM(S): Mus musculus 
2016-03-10 | E-GEOD-67918 | biostudies-arrayexpress
MetabolomicsImpact of myocardial reperfusion on human plasma lipidome
The primary aim of the study is to investigate the temporal changes in plasma lipidome before and after reperfusion in patients with ST-segment elevation myocardial infarction (STEMI) and their association with myocardial injury. We found that 56% of the identified lipid species were significantly a...
2022-02-07 | MTBLS3839 | MetaboLights
MetabolomicsMechanism of interventional effect and targets of Zhuyu Pill in regulating and suppressing colitis and cholestasis

Zhuyu pill (ZYP) is a traditional Chinese medicine prescription composed of two drugs, Coptis chinensis Franch. and Tetradium ruticarpum (A. Jussieu) T. G. Hartley, and is commonly used in the clinical treatment of diseases of the digestive system. However, the mechanism underly...

2022-11-02 | MTBLS4980 | MetaboLights
MetabolomicsIdentification of Metabolites and Transcripts Involved in Salt Stress and Recovery in Peanut
Peanut (Arachis hypogaea L.) is considered as a moderately salt-sensitive species and thus soil salinity can be a limiting factor for peanut cultivation. To gain insights into peanut plant physiology in response to salt stress and alleviation, we comprehensively characterized leaf relative electroly...
2019-03-19 | MTBLS583 | MetaboLights
TranscriptomicsExon Level Expression Profiling in D54 with or without TIP-1 expression
D54 stable cell lines that transfected with control shRNA and TIP-1 shRNA were cultured overnight. Isolated the total RNA of these cell lines to do microarray. Try to get more information about the difference in the mRNA level in these cell lines. We analyzed gene expression from 5 subjects: 2 contr...
ORGANISM(S): Homo sapiens 
2012-06-05 | E-GEOD-36116 | biostudies-arrayexpress
UnknownHigh quality draft genome sequence and analysis of Pontibacter roseus type strain SRC-1(T) (DSM 17521(T)) isolated from muddy waters of a drainage system in Chandigarh, India.
Not available
S-EPMC4511580 | biostudies-literature
TranscriptomicsTime-varying expression data from WI38 cell lines that were exposed to a challenge dose with or without a priming dose
The purpose of this experiment is to elucidate temporal activities and biological processes that can be inferred in response to a 200cGy challenging dose with or without a 10 cGy priming dose in embryonic human fibroblasts The experiment is designed around the human diploid embryonic lung fibroblast...
ORGANISM(S): Homo sapiens 
2012-04-30 | E-GEOD-37668 | biostudies-arrayexpress
ProteomicsParabiosis Suppresses Breast Tumor Growth With Increased Effector Memory T Cells and HSPB3
To evaluate anti-tumor effects of parabiosis followed by breast tumor cells re-challenge, breast tumor cells were injected to fourth mammary gland in one mouse of parabiosis mice. After 28 days, tumor cells were re-challenged to the other mice without tumor from separated parabiosis mice (Separant-t...
ORGANISM(S): Mus musculus (Mouse) 
2026-08-04 | PXD045474 | Pride
Anti-tumor Parabiosis Memory b cells Memory t cells Hspb3 
UnknownShuang-Huang-Lian prevents basophilic granulocyte activation to suppress Th2 immunity.
Not available
S-EPMC5753509 | biostudies-literature
MetabolomicsStage-specific roles of microbial dysbiosis and metabolic disorders in rheumatoid arthritis

OBJECTIVE: Rheumatoid arthritis (RA) is a progressive disease including four stages, where gut microbiome is associated with pathogenesis. We aimed to investigate stage-specific roles of microbial dysbiosis and metabolic disorders in RA.

METHODS: We investi...

2023-01-31 | MTBLS5297 | MetaboLights
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