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Aberrant DNA hypermethylation of CpG island (CGI) promoters are associated with transcriptional repression of many tumor suppressor genes and lead to tumor progression in many cancers. Most recently, one research group observed that aberrantly hypermethylated genes in multiple cancers are already re...
ORGANISM(S): Homo sapiens 
The model describing that aberrant CpG island (CGI) methylation leads to transcription repression of tumor suppressor genes and thereby is implicated in tumor progression has been established in many cancers. However, recent studies indicated aberrantly hypermethylated genes in multiple cancers are ...
ORGANISM(S): Homo sapiens 
We sequenced 205 patients who were suffering NSCLC with Exome sequencing method.
We sequenced 292 patients who were suffering NSCLC with Whole genome sequencing or Exome sequencing method.
The landscape of genetic alterations in lung adenocarcinoma derived from Asian patients is largely uncharacterized. Here we present an integrated genomic and transcriptomic analysis of 335 primary lung adenocarcinomas and 35 corresponding lymph node metastases from Chinese patients. Altogether 13 si...
Data Access Committee EGAC00001000177
In this study, unstimulated saliva samples were collected from 30 children (age 10-12 years) with no dental caries (NDC, n=10), low dental caries (LDC, n=10), and high dental caries (HDC, n=10). Salivary proteins were extracted, reduced, alkylated, trypsin digested and labeled with isobaric tags for...
ORGANISM(S): Homo Sapiens 
2017-12-19 | PXD008488 |
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