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UnknownStructure, regulation, signaling, and targeting of abl kinases in cancer.
Not available
S-EPMC3513796 | biostudies-literature
UnknownThe e13a3 (b2a3) and e14a3 (b3a3) BCR::ABL1 isoforms are resistant to asciminib.
Not available
S-EPMC11347367 | biostudies-literature
ProteomicsFunctional proteomics defines differential signaling networks of the oncogenic kinases Bcr-Abl p210 and p185
The two major isoforms of the oncogenic Bcr-Abl tyrosine kinase, p210 and p185, are expressed upon the Philadelphia chromosome translocation. p210 is the hallmark of chronic myelogenous leukemia, whereas p185 occurs in the majority of B-cell acute lymphoblastic leukemia. Differences in protein-prote...
ORGANISM(S): Mus musculus (Mouse) 
2017-01-31 | PXD005149 | Pride
Leukemia Bcr-abl tyrosine kinase Interactome Silac Phosphoproteome 
UnknownSynthesis of the l- and d-SH2 domain of the leukaemia oncogene Bcr-Abl.
Not available
S-EPMC9347351 | biostudies-literature
UnknownTargeted Protein Degradation through Cytosolic Delivery of Monobody Binders Using Bacterial Toxins.
Not available
S-EPMC7316569 | biostudies-literature
UnknownMonobodies as enabling tools for structural and mechanistic biology.
Not available
S-EPMC7370805 | biostudies-literature
UnknownThe growing arsenal of ATP-competitive and allosteric inhibitors of BCR-ABL.
Not available
S-EPMC3517953 | biostudies-literature
ProteomicsTandem affinity purification of monobodies against STAT3
The aim of the proteomics experiment was to determine the specificity of the generated monobodies for the target protein STAT3. This was done in an affinity-enrichment experiment using two endogenously expressed and tandem-affinity-tagged monobodies in two different cell lines (Jurkat and K562). Elu...
ORGANISM(S): Homo sapiens (Human) 
2020-07-10 | PXD018374 | Pride
Monobody Stat3 Tap Lc-ms/ms 
UnknownBioSITe: A Method for Direct Detection and Quantitation of Site-Specific Biotinylation.
Not available
S-EPMC6092923 | biostudies-literature
UnknownBCR-ABL1 compound mutants display differential and dose-dependent responses to ponatinib.
Not available
S-EPMC5777206 | biostudies-literature
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