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Transcriptomicssingle cell RNAseq of memory B cells in the context of rituximab-treated ITP patients
Rituximab (RTX) is widely used as a first-line therapeutic strategy in B cell-mediated autoimmune diseases. However, a large proportion of patients either do not respond to the treatment or relapse during B cell reconstitution. Primary immune thrombocytopenia (ITP) is a prototypic B cell mediated au...
ORGANISM(S): Homo sapiens 
2021-01-31 | E-MTAB-9955 | biostudies-arrayexpress
TranscriptomicsscRNASeq of Naïve, GC, plasma, memory B cells sorted from WT and Fip200-deficient mice spleen
We have employed a scRANSeq to study the difference between WT and Fip200-deficient B cell populations from mice spleen 11 days after immunization. FIP200 plays an important role in regulating LC3-dependent and LC3-independent autophage pathway, which is crucial for B cell development and differenti...
ORGANISM(S): Mus musculus 
2025-11-25 | E-MTAB-16123 | biostudies-arrayexpress
ModelsOuyang2014 - photomorphogenic UV-B signalling network
Ouyang2014 - photomorphogenic UV-B signalling network This model is described in the article: Coordinated photomorphogenic UV-B signaling network captured by mathematical modeling. Ouyang X, Huang X, Jin X, Chen Z, Yang P, Ge H, Li S, Deng XW. Proc. Natl. Acad. Sci. U.S.A. 201...
2024-09-02 | BIOMD0000000545 | BioModels
TranscriptomicsLongitudinal scRNAseq profiling of memory B cells in severe COVID19 patients
Memory B cells play a fundamental role in host defences against viruses. This dataset aimed at understanding their maturation and stability in the context of SARS-CoV-2 infection and consist of a longitudinal single-cell and repertoire profiling of the B cell response up to six months in four severe...
ORGANISM(S): Homo sapiens 
2021-01-31 | E-MTAB-9995 | biostudies-arrayexpress
TranscriptomicsLongitudinal scRNAseq profiling of memory B cells in mRNA vaccinated individuals post BA.1-breakthrough infection
Memory B cells play a fundamental role in host defenses against viruses. This dataset aimed at understanding the recruitment and remodeling of the memory B cell repertoire in the context of BA.1-breakthrough infection in BNT162b2 mRNA vaccinated individuals. All four donors enrolled in the study had...
ORGANISM(S): Homo sapiens 
2023-08-15 | E-MTAB-12651 | biostudies-arrayexpress
TranscriptomicsHuman B cell receptor light chain repertoire analysis in healthy individuals and SLE patients
Determination of expression levels of light chain V genes in peripheral blood B cells after FACS sorting for two populations of B cells (CD20+CD138-IgKappa+IgLambda- and CD20+CD138-IgKappa-IgLambda+). Analysis was performed on healthy individuals and SLE patients with analysis performed using sever...
ORGANISM(S): Homo sapiens 
2013-09-01 | E-GEOD-33544 | biostudies-arrayexpress
UnknownGenome sequence and transcriptomic profiles of a marine bacterium, Pseudoalteromonas agarivorans Hao 2018.
Not available
S-EPMC6437646 | biostudies-literature
TranscriptomicsTranscriptome analysis of Cryptococcus neoformans strain H99 in response to exposure to amphotericin B
Log phase of Cryptococcus neoformans strain H99 was exposed to amphotericin B (1.5μg/ml) or vehicle (control) for 3h. Transcriptome of drug treated cells were compared to no treatment cells.
ORGANISM(S): Cryptococcus neoformans var. grubii H99 
2023-08-16 | E-MTAB-12683 | biostudies-arrayexpress
TranscriptomicsB-type lamins differentially associate with specific genes during differentiation without directly affecting their expression
B-type lamins, the major structural component of the nuclear lamina, is thought to play a repressive role in the expression of many of its bound genes whose silencing are known to be critical for cell differentiation during early development. Using global mapping of lamin-B-chromatin interaction, w...
ORGANISM(S): Mus musculus 
2011-10-31 | E-GEOD-24532 | biostudies-arrayexpress
UnknownConstruction of efficient virus removal and micropropagation system for 'Yu Tai Yi Hao' chrysanthemum.
Not available
S-EPMC12603245 | biostudies-literature
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