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ProteomicsQuantitative proteomic and phosphoproteomic profiling of lung and heart tissues from Pulmonary arterial hypertension model rats
TMT-based quantitative proteomics was performed on lung tissues derived from SD rats which were treated with monocrotaline （MCT） for 1to 4 weeks. Similar analysis was performed with RV tissues from rats treated with MCT for 3 weeks. In addition, phosphoproteomic analysis was performed with lung and ...
ORGANISM(S): Rattus Norvegicus 
2022-11-25 | PXD038462 |
UnknownSplicing function of mitotic regulators links R-loop–mediated DNA damage to tumor cell killing
Not available
S-JCBD-201409073 | bioimages
ProteomicsChemoproteomic Mapping of the Glycolytic Targetome in Cancer Cells
we report a Target Responsive Accessibility Profiling (TRAP) approach for the global and quantitative analysis of glycolytic metabolites targetome in native cancer cell milieu.
ORGANISM(S): Homo Sapiens 
2020-11-17 | PXD022568 |
ProteomicsCullin 4b modulates Wnt signaling and CRL4b targets Irgm1 to fuel intestinal stem cell stemness and niche
Background & Aims: Hierarchical organization of intestine relies on their stem cells by self-renew and producing committed progenitors. Although signals like Wnt are known to animate the continued renewal by maintaining intestinal stem cells (ISCs) activity, molecular mechanisms especially E3 ubiqui...
ORGANISM(S): Mus musculus (Mouse) 
2022-08-11 | PXD021528 | Pride
Cul4b  intestinal stem cells (iscs)  irgm1  stem cell niche 
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