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ProteomicsStudy on the spatial effect of peripheral ApoE3 on regulating cadmium binding proteome and mechanism of cognitive impairment in the elderly
The experiment utilized a total of 54 five-week-old Sprague-Dawley rats, each weighing approximately 100 grams. These rats were randomly divided into 9 groups, consisting of 27 female and 27 male rats. Based on the intervention dose of cadmium (Cd), the rats were further randomly assigned into 3 mai...
ORGANISM(S): Rattus Rattus 
2025-04-16 | PXD063013 |
ProteomicsDisruption of MerTK Increases the Efficacy of Checkpoint Inhibitor by Enhancing Ferroptosis and Immune Response in Hepatocellular Carcinoma
To investigate the potentail anti-PD-L1 resistance mechanism in HCC, we examine the different proteins between hepa1-6 and res1-6 tumor cells. Proteins were digested with trypsin and following by high-resolution liquidchromatography-tandem MS(LC-MS/MS) analysis
ORGANISM(S): Mus Musculus 
2023-12-21 | PXD048069 |
ProteomicsThe targets study of HDCA in ameliorating NAFLD induced by high-calories diet by multi-omics technology
HDCA supplementation ameliorated diet-induced NAFLD in C57 wild type mice. In attempt to comprehensively understand the molecular mechanism occurring during the protective effect of HDCA, transcriptomic and proteomic profiles of mouse liver were first analyzed utilizing RNA-Sequencing and Tandem Mas...
ORGANISM(S): Mus Musculus 
2023-08-18 | PXD044613 |
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