Bacterial protein glycosylation can be mediated by oligosaccharyltransferases (OTases) that transfer a preassembled lipid-linked oligosaccharide or polysaccharide en bloc to acceptor proteins. O-linking OTases transfer O-antigen or capsular polysaccharides to the side chains of serine or threonine r...
This work explore the optimisation of PglS to allow the improved production of glycoproteins modified with Streptococcus agalactiae associated capsule glycans.