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TranscriptomicsAn Advancement in Developmental and Reproductive Toxicity (DART) Risk Assessment: Evaluation of a Bioactivity and Exposure-Based NAM Toolbox
High throughput transcriptomics using the TempO-Seq (TM) platform for dose response modelling of 3 different cell lines treated with multiple compounds as part of a study to generate a toolbox and workflow for non-animal safety assessments. The data generated here was produced as one part of a toolb...
ORGANISM(S): Homo sapiens 
2025-09-15 | E-MTAB-15274 | biostudies-arrayexpress
TranscriptomicsComparison of gene expression during meiosis between wild-type and rad50-deficient strains of Coprinopsis cinerea
Meiosis was compared in rad50-1 and wild type strains of C. cinerea at 6 time points spanning the meiotic timecourse. Abstract: The basidiomycete Coprinopsis cinerea is well-suited to studies of meiosis because meiosis progresses synchronously in ten million cells within each mushroom cap. Approxima...
ORGANISM(S): Coprinopsis cinerea 
2012-05-14 | E-GEOD-37942 | biostudies-arrayexpress
GenomicsRRBS of human fetal testis treated to a mixture of DEHP/BPA
Fetal human fetal testes (8-11 weeks post-fertilization [WPF]) were cut into small pieces (~1 mm3 ) and 4-6 pieces/testis (depending of the age or size of the gonad) were insert into the muscle of the left back of two twin female mice. One week after surgery, one mouse was exposed by drinking water ...
ORGANISM(S): Homo sapiens 
2026-01-01 | E-MTAB-13840 | biostudies-arrayexpress
TranscriptomicsWhole blood RNA-Sequencing from an Influenza H3N2 human challenge model
The Influenza H3N2 human challenge model has been described in detail previously5. Briefly, 20 healthy volunteers were inoculated intranasally with a standardized dose of Influenza A virus (A/Belgium/4217/2015(H3N2)) under quarantine conditions. From 24 hours after inoculation, virus was quantified ...
ORGANISM(S): Homo sapiens 
2025-05-26 | E-MTAB-13041 | biostudies-arrayexpress
MetabolomicsUntargeted metabolomics profiling reveals exercise intensity-dependent alterations in Thoroughbred racehorses’ plasma after routine conditioning sessions

Thoroughbred (TB) racehorses are subjected to rigorous conditioning programs involving exercise sessions of various types, distances and intensities. These programs aim to optimize both their physical and mental capabilities, which are essential to achieve maximal performance. Conventional invest...

2024-01-16 | MTBLS8285 | MetaboLights
Genomics37a30206-29b3-47a0-90c4-eee326fe5b8b - samples
Genotype calls for 83 Aboriginal Australian genomes split by chromosomes. In short, genotypes were called individually with samtools. They were subsequently filtered with thresholds related to sequencing depth, location of variants, sequencing error, and strand bias. Once combined, the genotypes wer...
EGAD00001004155 | EGA
MetabolomicsNitisinone’s mosquitocidal properties hold promise for malaria control

Nitisinone’s mosquitocidal properties hold promise for malaria control

2025-06-16 | MTBLS11617 | MetaboLights
TranscriptomicsmicroRNA-155 is an Epstein-Barr Virus induced gene that modulates EBV-regulated gene expression (microRNA-155 infection)
The cellular microRNA, miR-155 has been shown to be involved in lymphocyte activation and is expressed in EBV infected cells displaying type III latency gene expression but not type I latency gene expression. We show here that the elevated levels of miR-155 in type III latency cells is due to EBV g...
ORGANISM(S): Homo sapiens 
2008-03-17 | E-GEOD-10864 | biostudies-arrayexpress
TranscriptomicsExpression data from MMTV-PDK1 transgenic mice
The role of PDK1 on mammary tumorigenesis and its interaction with PPARdelta, was assessed. Transgenic mice were generated in which PDK1 was expressed in the mammary epithelium. We used microarrays to analyse global gene expression changes in MMTV-PDK1 transgenic mice versus wild-type mice and deter...
ORGANISM(S): Mus musculus 
2011-02-05 | E-GEOD-27083 | biostudies-arrayexpress
TranscriptomicsRNA-seq of murine cytotoxic T lymphocytes in response to myosin IIA inhibition using para-nitroblebbistatin
This project explores the effects of inhibiting myosin IIA using para-nitroblebbistatin (pNB) on effector cytotoxic T lymphocyte (CTL) activation. Effector CTLs were differentiated from OTI TCR transgenic mice for 7 days in vitro, then stimulated (or not stimulated) with anti-CD3 for 1 hour, treated...
ORGANISM(S): Mus musculus 
2025-09-27 | E-MTAB-14579 | biostudies-arrayexpress
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