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UnknownVariants in ARID5B gene are associated with the development of acute lymphoblastic leukemia in Mexican children.
Not available
S-EPMC11486264 | biostudies-literature
Transcriptomics10x single cell mRNA sequencing of transcervical swabs of pregnant donors at 5.2, 7.6, and 10.2 weeks of gestation
Non-invasive prenatal testing (NIPT) using cell free fetal DNA has transformed prenatal care by allowing risk assessment for a number of fetal genetic conditions without posing risk to the pregnancy. However, its limitations, including low fetal fraction and high DNA fragmentation, restrict its capa...
ORGANISM(S): Homo sapiens 
2026-05-31 | E-MTAB-15846 | biostudies-arrayexpress
TranscriptomicsmicroRNA suppresses prostate cancer stem cells and metastasis by inhibiting a cohort of pro-metastasis targets including CD44, Rho GTPases and EZH2
microRNA plays important roles in tumor initiation and progression. Here we showed that, one of the miR-200 family member, miR-141 is drastically under-expressed in several prostate cancer stem cell populations in both xenograft and primary patient samples. Enforced expression of miR-141 in CD44+ PC...
ORGANISM(S): Homo sapiens 
2016-08-15 | E-GEOD-71756 | biostudies-arrayexpress
TranscriptomicsmiRNA expression of 3 prostate cell types from human normal donors
Prostate primary epithelial and stromal cells were isolated from normal donorhuman prostate tissue and patient prostate tumors (>Gleason 8) using in vitroselective media conditions and differential substrate adhesion properties.Tumor cells specific to the prostate epithelial cell component attached ...
ORGANISM(S): Homo sapiens 
2015-07-01 | E-GEOD-17323 | biostudies-arrayexpress
TranscriptomicsEWS/WT1 co-operates with the loss of p53 to exert its oncogenic effects and up-regulates canonical Wnt pathway signaling.
The t(11;22)(p13;q12) translocation is pathognomonic for the highly aggressive desmoplastic small round cell tumour (DSRCT). The translocation fuses exon 7 of the EWS gene to exon 8 of the WT1 gene (EWS/WT1). Two splice variants of EWS/WT1 exist, arising from the presence (+KTS) or absence (-KTS) of...
ORGANISM(S): Mus musculus 
2014-11-01 | E-GEOD-42649 | biostudies-arrayexpress
UnknownHydrolyzed infant formula and early β-cell autoimmunity: a randomized clinical trial.
Not available
S-EPMC4225544 | biostudies-literature
UnknownSimvastatin in Critically Ill Patients with Covid-19.
Not available
S-EPMC10755839 | biostudies-literature
UnknownSiblings with ischemic stroke study: results of a genome-wide scan for stroke loci.
Not available
S-EPMC3251509 | biostudies-literature
UnknownAssociation of LRRK2 p.A419V with Parkinson's Disease in East Asians and analysis of age at onset.
Not available
S-EPMC12913921 | biostudies-literature
UnknownLarge-scale genetic characterization of Parkinson's disease in the African and African admixed populations.
Not available
S-EPMC11759243 | biostudies-literature
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