Hardy Todd A TA

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Whole genome profile of SWNCT and MWCNT vs. asbestos subchronic exposures to human small airway epithelial cells

Recent in vivo studies reported that inhaled carbon nanotube distribute in the alveolar region resulting in an acute inflammation, progressive fibrotic response and particle accumulation at the bronchoalveolar junction with low clearance. With similar biopersistence and shape as asbestos, a known l...

ORGANISM(S): Homo sapiens

2013-07-22 | E-GEOD-41178 | biostudies-arrayexpress

MicroRNA-15/16 Antagonizes c-Myb to Control Natural Killer Cell Maturation

NK cells develop in the bone marrow and complete their maturation in peripheral organs, but the molecular events controlling maturation are incompletely understood. Utilizing an NK cell-specific miR-15/16 deficient genetic model (15aKO), we identified a critical role for miR-15/16 family microRNAs i...

ORGANISM(S): Mus musculus

2015-09-03 | E-GEOD-55033 | biostudies-arrayexpress

Linking protective GAB2 variants, increased cortical GAB2 expression and decreased Alzheimer's disease pathology.

Not available

S-EPMC3665686 | biostudies-literature

A novel Alzheimer disease locus located near the gene encoding tau protein.

Not available

S-EPMC4573764 | biostudies-literature

Associations between Potentially Modifiable Risk Factors and Alzheimer Disease: A Mendelian Randomization Study.

Not available

S-EPMC4469461 | biostudies-literature

A prognostic model for use before elective surgery to estimate the risk of postoperative pulmonary complications (GSU-Pulmonary Score): a development and validation study in three international cohorts.