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Microarrays analysis identifies WNT16in senescent fibroblasts. To identify genes expressed in replicative senescence, microarray experiments were conducted in which we compared the RNA expression profile of young MRC5 fibroblasts at population doubling 28 (PDL28) and replicative senescent MRC5 fibro...
ORGANISM(S): Homo sapiens 
The goal of this study was to identify microRNAs that were differentially expressed in colon tumors and determine if microRNA expression profiles could predict poor cancer survival. Keywords: disease state design For these experiments, we used RNA extracted from pairs of colon adenocarcinoma tissue ...
ORGANISM(S): Homo sapiens 
Lung cancer remains the most common cause of cancer deaths worldwide, yet there is currently a lack of diagnostic noninvasive biomarkers that could guide treatment decisions. Small molecules (<1500 Da) were measured in urine collected from 469 lung cancer patients and 536 population controls using u...
2014-05-06 | MTBLS28 | MetaboLights
We compared the expression of microRNAs in primary colon tumors with their paired liver metastases using the Nanostring human microRNA assays version 1 23 microRNAs were found to be differentially expressed between colon primary tumors and their paired metastases Total mRNA was extracted from flash ...
ORGANISM(S): Homo sapiens 
microRNA expression profiling of Stage I Lung Adenocarcinoma and non-tumor adjacent tissues. The Nanostring nCounter Human miRNA Expression Assay Kit version 1.6 (Nanostring, Seattle, WA) was used to obtain microRNA profiles of tumor and adjacent non-tumor tissues excised from Stage I Lung Adenocarc...
ORGANISM(S): Homo sapiens 
Genome wide DNA methylation profiling of Stage I Lung Adenocarcinoma and non-tumor adjacent tissues. The Illumina Infinium 27k Human DNA methylation Beadchip was used to obtain DNA methylation profiles across approximately 27,000 CpGs. Samples included tumor and adjacent non-tumor tissues excised fr...
ORGANISM(S): Homo sapiens 
This dataset is the mRNA expression for Stage I Lung Adenocarcinoma and non-tumor adjacent tissues also characterized by Genome-wide DNA methylation profiling. Total cellular RNA was extracted from tumor and matching adjacent non-tumor lung and hybridized to Illumina HumanRef-8 v3 Expression Beadchi...
ORGANISM(S): Homo sapiens 
95 microRNA probes were found to have altered expression in colon adenomas compared to paired non-adenoma tissue Total mRNA was extracted from colon tissue that was flash frozen immediately after surgery. A total of 36 tissues were used for microarray analysis. Briefly, 5 ug of RNA were biotin lab...
ORGANISM(S): Homo sapiens 
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