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TranscriptomicsDiscovery of novel recurrent mutations and rearrangements in early T-cell precursor acute lymphoblastic leukemia by whole genome sequencing
Early T-cell precursor acute lymphoblastic leukaemia (ETP ALL) is an aggressive malignancy of unknown genetic basis. We performed whole genome sequencing of tumour and normal DNA from 12 children with ETP ALL and assessed the frequency of somatic alterations in 52 ETP and 42 non-ETP T-ALL samples by...
ORGANISM(S): Homo sapiens 
2011-11-23 | E-GEOD-28703 | biostudies-arrayexpress
ProteomicsCharacterization of Mast2 Kinase Defines Structural Features, Regulation, and Substrates
The mammalian microtubule-associated serine/threonine (MAST) kinases are a highly conserved subfamily of AGC kinases that are implicated as therapeutic targets for cancer and diabetes. However, the activity, regulation, and substrates of MAST kinases are poorly understood. Stable 18O-ATP labeled kin...
ORGANISM(S): Homo sapiens (Human) 
2026-01-05 | PXD069171 | Pride
Human Mast2 Sikalip 
GenomicsThe genomic complexity of early T-cell progenitor acute lymphoblastic leukemia

CREST

The accurate identification of structural variations using whole-genome DNA sequencing data generated by next-generation sequencing technology is extremely difficult. To address this challenge, we have developed CREST, an algorithm that uses sequencing reads with partial align...

phs000340.v2.p1 | EGA
TranscriptomicsThe rectal cancer microRNAome - a comprehensive comparative analysis of microRNA expression in rectal cancer and matched normal mucosa
Purpose: MicroRNAs play a prominent role in a variety of physiological and pathological biological processes, including cancer. For rectal cancers, only limited data are available on microRNA expression profiles, while the underlying genomic and transcriptomic aberrations have been firmly establishe...
ORGANISM(S): Homo sapiens 
2012-10-05 | E-GEOD-38389 | biostudies-arrayexpress
UnknownConcurrent RB1 Loss and BRCA Deficiency Predicts Enhanced Immunologic Response and Long-term Survival in Tubo-ovarian High-grade Serous Carcinoma.
Not available
S-EPMC11325151 | biostudies-literature
UnknownLiraglutide and Cardiovascular Outcomes in Type 2 Diabetes.
Not available
S-EPMC4985288 | biostudies-literature
UnknownIntegrative analysis of 111 reference human epigenomes.
Not available
S-EPMC4530010 | biostudies-literature
UnknownLifetime ovulatory years and risk of epithelial ovarian cancer: a multinational pooled analysis.
Not available
S-EPMC10165492 | biostudies-literature
UnknownConcurrent RB1 loss and <i>BRCA</i>-deficiency predicts enhanced immunological response and long-term survival in tubo-ovarian high-grade serous carcinoma.
Not available
S-EPMC10659507 | biostudies-literature
UnknownFeatures of acute COVID-19 associated with post-acute sequelae of SARS-CoV-2 phenotypes: results from the IMPACC study.
Not available
S-EPMC10764789 | biostudies-literature
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