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ProteomicsCharacterization of Mast2 Kinase Defines Structural Features, Regulation, and Substrates
The mammalian microtubule-associated serine/threonine (MAST) kinases are a highly conserved subfamily of AGC kinases that are implicated as therapeutic targets for cancer and diabetes. However, the activity, regulation, and substrates of MAST kinases are poorly understood. Stable 18O-ATP labeled kin...
ORGANISM(S): Homo sapiens (Human) 
2026-01-05 | PXD069171 | Pride
Human Mast2 Sikalip 
ProteomicsMolecular Basis of the mechanisms controlling MASTL - Proteomics analysis of MASTL substrate proteome and phosphorylation state
As part of our study on human MASTL (microtubule-associated serine/threonine kinase-like), we used mass spectrometry (MS)-based proteomics in the aim to unravel novel aspects about MASTL activation, regulation and potential substrates. Specifically, we performed a phosphoproteomics-based kinase assa...
ORGANISM(S): Homo sapiens (Human) 
2020-01-09 | PXD007991 | Pride
Human Lc-msms Mastl 
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