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TranscriptomicsInvestigation of barley brittle stem mutants
The barley brittle stem mutants, fs2, designated X054 and M245, have reduced levels of cellulose compared with their isogenic parents Ohichi and Shiroseto. A custom-designed microarray, based on Agilent technology and including genes involved in cell wall metabolism, was used to compare transcript ...
ORGANISM(S): Hordeum vulgare 
2010-07-23 | E-GEOD-17873 | biostudies-arrayexpress
TranscriptomicsMIWI catalysis is required for piRNA amplification-independent LINE1 transposon silencing [deep sequencing]
Here we show that MIWI is a small RNA-guided ribonuclease (Slicer) that requires extensive complementarity for target cleavage in vitro. Disruption of its catalytic activity in mice by a single point mutation results in male infertility and displays increased accumulation of LINE1 transposon transcr...
ORGANISM(S): Mus musculus 
2011-11-30 | E-GEOD-32184 | biostudies-arrayexpress
UnknownSingle-cell transcriptomics of suprachiasmatic nuclei reveal a Prokineticin-driven circadian network
Not available
S-SCDT-EMBOJ-2021-108614 | biostudies-other
TranscriptomicsMIWI catalysis is required for piRNA amplification-independent LINE1 transposon silencing [microarray]
Here we show that MIWI is a small RNA-guided ribonuclease (Slicer) that requires extensive complementarity for target cleavage in vitro. Disruption of its catalytic activity in mice by a single point mutation results in male infertility and displays increased accumulation of LINE1 transposon transcr...
ORGANISM(S): Mus musculus 
2011-11-30 | E-GEOD-32180 | biostudies-arrayexpress
TranscriptomicsmiR-28 expression in the Burkitt lymphoma cell line P3HR1
Burkitt lymphoma (BL) is a highly aggressive B cell non-Hodgkin lymphoma (B-NHL), which originates from germinal center (GC) B cells and harbors translocations deregulating the MYC oncogene. A comparative analysis of microRNAs (miRNAs) expressed in normal and malignant GC B cells identified miR-28 a...
ORGANISM(S): Homo sapiens 
2014-06-01 | E-GEOD-56268 | biostudies-arrayexpress
UnknownQuantitative measures of clock protein dynamics in the mouse suprachiasmatic nucleus extends the circadian time-keeping model
Not available
S-SCDT-10_1038-S44318-025-00426-Z | biostudies-other
TranscriptomicsMIWI catalysis is required for piRNA amplification-independent LINE1 transposon silencing
This SuperSeries is composed of the following subset Series: GSE32180: MIWI catalysis is required for piRNA amplification-independent LINE1 transposon silencing [microarray] GSE32184: MIWI catalysis is required for piRNA amplification-independent LINE1 transposon silencing [deep sequencing] Refer to...
ORGANISM(S): Mus musculus 
2011-11-30 | E-GEOD-32183 | biostudies-arrayexpress
TranscriptomicsGenome-wide studies of histone Me2 SWIRM and polyamine oxidase domain homologues of mammalian LSD1
In order to gain a more global view of the activity of histone demethylases we report here studies of the two fission yeast SWIRM and polyamine oxidase domain homologues of mammalian LSD1. Consistent with previous work (Nicolas et al., 2006) we find that the two S. pombe proteins, which we name Swm...
ORGANISM(S): Schizosaccharomyces pombe 
2010-05-27 | E-GEOD-6224 | biostudies-arrayexpress
UnknownExome sequencing for patients with developmental and epileptic encephalopathies in clinical practice.
Not available
S-EPMC10952465 | biostudies-literature
UnknownGWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19.
Not available
S-EPMC10208981 | biostudies-literature
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