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TranscriptomicsORNL 5wk Hr(n)/+ mice skin array
This array is spotted in house in order to survey the interested genes expressed mainly in skin with the selection of the clones from Research Genetics. Keywords: Genetic Mutant 5 week-old heterozygous Hr(n) mutant mice vs wild-type mice was used in the microarray. Four biological replicates were i...
ORGANISM(S): Mus musculus 
2010-07-01 | E-GEOD-4053 | biostudies-arrayexpress
TranscriptomicsMicroRNA profiling of human HeLa cells overexpressing p19 H-Ras
MicroRNA miRNA expression profiles for human HeLa cells (Cervical cancer), overexpressing p19 H-Ras, were examined to investigate the miRNA regulation by p19 H-Ras. miRNA microarray analysis identified statistical unique profiles, which could discriminate miRNAs regulated by p19 H-Ras and not regul...
ORGANISM(S): Homo sapiens 
2008-12-12 | E-TABM-494 | biostudies-arrayexpress
TranscriptomicsDe novo characterization of foliar transcriptome in Chenopodium amaranticolor and analysis of the differentially expressed genes during the stage of hypersensative response induced by distinct plant viruses
The hypersensitive response (HR) system of Chenopodium spp. confers broad-spectrum virus resistance. However, scant knowledge exists at the genomic level for Chenopodium, thus impeding the advanced molecular research of this attractive feature. Hence we took advantage of RNA-seq to survey the foliar...
ORGANISM(S): Chenopodium amaranticolor 
2013-02-20 | E-GEOD-38451 | biostudies-arrayexpress
TranscriptomicsQuality Control in Microarray Assessment of Gene Expression in Human Airway Epithelium
Microarray technology provides a powerful tool for defining gene expression profiles of airway epithelium that lend insight into the pathogenesis of human airway disorders. The focus of this study was to establish rigorous quality control parameters to ensure that microarray assessment of the airway...
ORGANISM(S): Homo sapiens 
2010-09-19 | E-GEOD-11906 | biostudies-arrayexpress
MetabolomicsFecal microbiota transplantation plus anti-PD-1 immunotherapy in advanced melanoma: a phase I trial

Fecal microbiota transplantation (FMT) represents a potential strategy to overcome resistance to immune checkpoint inhibitors in patients with refractory melanoma; however, the role of FMT in first-line treatment settings has not been evaluated. We conducted a multicenter phase I trial combining ...

2025-02-27 | MTBLS711 | MetaboLights
TranscriptomicsBreastPRS is a Gene Expression Assay that Stratifies Intermediate-Risk Oncotype DX Patients into High or Low-Risk for Disease Recurrence
Molecular prognostic assays, such as Oncotype DX, are increasingly incorporated into the management of patients with invasive breast carcinoma. BreastPRS is a new molecular assay developed and validated from a meta-analysis of publically available genomic datasets. We applied the assay to matched fr...
ORGANISM(S): Homo sapiens 
2013-06-23 | E-GEOD-47109 | biostudies-arrayexpress
TranscriptomicsExpression data from Saccharomyces cerevisae strains deleted for the RNA-binding hnRNP Npl3
Transcription is a major obstacle for replication fork progression and a cause of genome instability. Such instability increases in mutants with a suboptimal assembly of the nascent messenger ribonucleo-protein particle (mRNP), as THO/TREX and some heterogeneous nuclear ribonucleoproteins (hnRNPs) m...
ORGANISM(S): Saccharomyces cerevisiae 
2013-11-15 | E-GEOD-50186 | biostudies-arrayexpress
TranscriptomicsCigarette Smoking Induces Overexpression of a Fat Depleting Gene AZGP1 in the Human Airway Epithelium
Smokers weigh less and have less body fat than non-smokers, and increased body fat and weight gain are observed following smoking cessation. To assess a possible molecular mechanism underlying the inverse association between smoking and body weight, we hypothesized that smoking may induce the expres...
ORGANISM(S): Homo sapiens 
2009-01-06 | E-GEOD-10135 | biostudies-arrayexpress
TranscriptomicsExpression data of germinating Arabidopsis seeds
In depth temporal profiling of transcript changes at 10 time points during germination in Arabidopsis seed was carried out. The time course utilised, encompassed seed maturation, stratification, germination and post-germination and provided a global investigation into the tightly regulated, phasic c...
ORGANISM(S): Arabidopsis thaliana 
2011-09-08 | E-GEOD-30223 | biostudies-arrayexpress
TranscriptomicsMicroarray for suspension cells of PA14 WT with and without NE (50 uM and 500 uM) for 7 h
It has been proposed that the gastro-intestinal tract environment containing high levels of neuroendocrine hormones is important for gut-derived P. aeruginosa infections. In this study, we report that the hormone norepinephrine increases P. aeruginosa PA14 growth, virulence factor production, invasi...
ORGANISM(S): Pseudomonas aeruginosa UCBPP-PA14 
2009-08-27 | E-GEOD-13326 | biostudies-arrayexpress
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