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UnknownGene-centric meta-analyses for central adiposity traits in up to 57 412 individuals of European descent confirm known loci and reveal several novel associations.
Not available
S-EPMC3988452 | biostudies-literature
TranscriptomicsArctic charr exposed to acute thermal stress
Arctic charr is an especially attractive aquaculture species given that it features the desirable tissue traits of other salmonids, but can be bred and grown at inland freshwater tank farms year round. It is therefore of interest to develop upper temperature tolerant (UTT) strains of Arctic charr to...
ORGANISM(S): Salmo salar 
2011-06-01 | E-GEOD-26306 | biostudies-arrayexpress
UnknownEpigenome-wide association study (EWAS) of BMI, BMI change and waist circumference in African American adults identifies multiple replicated loci.
Not available
S-EPMC4492394 | biostudies-literature
UnknownGenome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution.
Not available
S-EPMC2695778 | biostudies-literature
TranscriptomicsRescue of KRAS suppression in HCT116 colon cancer cell line
Cancer cells that express oncogenic alleles of RAS typically require sustained expression of the mutant allele for survival, but the molecular basis of this oncogene dependency remains incompletely understood. To identify genes that can functionally substitute for oncogenic RAS, we systematically ex...
ORGANISM(S): Homo sapiens 
2014-07-22 | E-GEOD-55942 | biostudies-arrayexpress
TranscriptomicsKRAS and YAP1 converge to regulate EMT and tumor survival
Cancer cells that express oncogenic alleles of RAS typically require sustained expression of the mutant allele for survival, but the molecular basis of this oncogene dependency remains incompletely understood. To identify genes that can functionally substitute for oncogenic RAS, we systematically ex...
ORGANISM(S): Mus musculus 
2014-07-27 | E-GEOD-56175 | biostudies-arrayexpress
UnknownDisease model discovery from 3,328 gene knockouts by The International Mouse Phenotyping Consortium.
Not available
S-EPMC5546242 | biostudies-literature
TranscriptomicsUndifferentiated Pleomorphic Sarcoma Model
Analysis of undifferentiated pleomorphic sarcoma/malignant fibrous histiocytoma-like tumors from LSL-KrasG12D, p53Fl/Fl mouse model of soft tissue sarcoma. Murine soft tissue sarcomas (n = 17) were compared to normal muscle (n = 4). Tumors were isolated surgically from soft tissue sarcomas generate...
ORGANISM(S): Mus musculus 
2010-03-03 | E-GEOD-16779 | biostudies-arrayexpress
UnknownImpact of essential genes on the success of genome editing experiments generating 3313 new genetically engineered mouse lines.
Not available
S-EPMC11443006 | biostudies-literature
UnknownControversies in acute kidney injury: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Conference.
Not available
S-EPMC8481001 | biostudies-literature
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