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MetabolomicsMetabolomic Characterization of Knock-Out Mutants in Arabidopsis - Development of a Metabolite Profiling Database for Knock-Out Mutants in Arabidopsis (MeKO)
Despite recent intensive research efforts in functional genomics, the functions of only a limited number of Arabidopsis (Arabidopsis thaliana) genes have been determined experimentally. Thus, improving gene annotation remains a major challenge in plant science. Because metabolite profiling can chara...
2014-03-01 | MTBLS47 | MetaboLights
TranscriptomicsRNA-seq of human monocytic cell line (THP-1) treated with compound #42 (2D216), LPS, #42(2D216)/LPS, or vehicle controls
To explore the effects of compound #42 on RNA transcription of THP-1 cells, we performed RNA-seq analysis.
ORGANISM(S): Homo sapiens 
2022-01-12 | E-MTAB-10222 | biostudies-arrayexpress
TranscriptomicsExpression data from HEK293 cells with or without MIBP1 overexpression
The transcription factor c-MYC intron binding protein 1 (MIBP1) binds to various genomic regulatory regions, including intron 1 of c-MYC. This factor is highly expressed in post-mitotic neurons in the fetal brain and may be involved in various biological steps, such as neurological and immunological...
ORGANISM(S): Homo sapiens 
2012-01-31 | E-GEOD-26420 | biostudies-arrayexpress
TranscriptomicsRNA-seq of human monocytic cell line (THP-1) treated with compound 81 or vehicle controls
To explore the effects of compound 81 on RNA transcription of THP-1 cells, we performed RNA-seq analysis.
ORGANISM(S): Homo sapiens 
2021-12-14 | E-MTAB-10269 | biostudies-arrayexpress
TranscriptomicsDefinitive haplotypes from a collection of complete hydatidiform moles (CHMs)
The haplotype map constructed by the International HapMap Project is a valuable source for the studies of disease genes, population structure, and evolution. In the Project, haplotypes have been inferred from experimentally determined genotypes, and are fairly accurate for Caucasians and Africans si...
ORGANISM(S): Homo sapiens 
2010-04-05 | E-GEOD-12713 | biostudies-arrayexpress
TranscriptomicsDefinitive SNP/CNV haplotype map of Asians determined using a collection of complete hydatidiform moles (Illumina)
Copy number variations (CNVs) are abundant, possibly variable among populations, and can confer various phenotypic variations such as risk to complex disease. We determined a genome-wide high resolution SNP/CNV haplotype structure of Asians, by analyzing a collection of complete hydatidiform moles (...
ORGANISM(S): Homo sapiens 
2010-05-17 | E-GEOD-18663 | biostudies-arrayexpress
TranscriptomicsTudor domain containing 12 (TDRD12) is essential for secondary piRNA biogenesis in mice
Piwi-interacting RNAs (piRNAs) are gonad-specific small RNAs that provide defence against transposable genetic elements called transposons. Our knowledge of piRNA biogenesis is sketchy, partly due to an incomplete inventory of the factors involved. Here, we identify Tudor domain-containing 12 (TDRD1...
ORGANISM(S): Mus musculus 
2013-11-04 | E-GEOD-50544 | biostudies-arrayexpress
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