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A high percentage of potential oncology drugs fail in clinical trials, partly because preclinical models used to test them are inadequate. Breast cancer is the leading cause of cancer-related death among women worldwide but we lack appropriate in vivo models for the ER+ subtypes, which represent mor...
ORGANISM(S): Homo sapiens 
The analysis identifies genes affected by RNF40 silencing in HCC1806 cells
ORGANISM(S): Homo sapiens 
The analysis identifies differentially occupied genomic regions of H2Bub1, H3K79me3, and H3K27ac by RNF40 silencing in HCC1806 cells
ORGANISM(S): Homo sapiens 
We generated two comprehensive large-scale proteomics datasets with deliberate batch effects using the latest parallel accumulation-serial fragmentation in both Data-Dependent and Data-Indepentdent Acquisition modes. This dataset contain a balanced two-class design (cell lines: HCC1806 vs HS578T), a...
ORGANISM(S): Homo sapiens (Human) 
2023-11-21 | PXD041391 | Pride
mRNA-seq of HCC1806 cells, treated with siControl or siRNF40 for 48 hours
The mechanisms behind drug resistance and sensitivity in breast cancers relies on complex signalling pathways that involve the up or downregulation of certain genes. Many of these genes are involved in adhesion, growth, epithelial/mesenchymal transitions, and apoptosis. We used microarrays to assess...
ORGANISM(S): Homo sapiens 
ChIP-seq of HCC1806 cells (H2Bub1, H3K79me3, H3K27ac), treated with siControl or siRNF40 for 48 hours
Immortalized human breast cancer cell line, HCC1806, was analyzed via RT-qPCR for transcript expression of selected cytokines and cytokine receptors associated with promotion of tumor vasculature and breast cancer metastasis
ORGANISM(S): Homo sapiens 
2016-05-06 | GSE80642 | GEO
Genomics
Breast cancer cells HCC1806 sequencing
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
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