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TranscriptomicsNormal human osteoblasts and Hs578t mono and coculture
As a model for investigating changes in gene expression in response to epithelial-osteoblast interactions in bone metastases of breast carcinomas, cells that represented malignant epithelial cell compartments (Hs578T) and cells that represented skeletal compartments (Normal Human (NH) Osteoblasts) w...
ORGANISM(S): Homo sapiens 
2012-01-06 | E-GEOD-29031 | biostudies-arrayexpress
GenomicsChIP-sequencing of ZEB1 in triple negative breast cancer cell line Hs578T
This experiment is performed to reveal the novel binding sites of ZEB1 transcription factor globally in triple negative breast cancer cell line Hs578T. We also reveal the effect of TGF cytokine on the binding sites of ZEB1.
ORGANISM(S): Homo sapiens 
2018-04-25 | E-MTAB-5241 | biostudies-arrayexpress
TranscriptomicsEpCAM expressing Hs578T cells
EpCAM is frequently overexpressed in human invasive breast cancer. We reported EpCAM overexpression to be an independent prognostic marker for poor overall survival in node-positive breast cancer. We used microarrays in order to investigate changes of the transcriptome on EpCAM gene overexpression i...
ORGANISM(S): Homo sapiens 
2010-12-02 | E-GEOD-25743 | biostudies-arrayexpress
TranscriptomicsTranscription profiling time series of HOXA5 induction in human Hs578T cell line
HOXA5 inducible cell line Hs578T was established and cultured as described previously (MCB 2004. 24:924-935). 2×106 cells were seeded onto a 10-cm cell culture dish at 24h before induction. Two batches of RNA from HOXA5-inducible cells (0 h, 6 h and 9 h) were purified for repeating the microarray h...
ORGANISM(S): Homo sapiens 
2007-08-25 | E-GEOD-2241 | biostudies-arrayexpress
ProteomicsLC-MS profiles of Hs578T cell extracts exposed to doxorubicin
This dataset contains LC-MS raw files of Hs578T cell extracts exposed to doxorubicin and controls for untargeted metabolomics as part of: A novel hybrid zwitterionic hydrophilic interaction liquid chromatography for untargeted metabolomics using rigorous metabolite identification approach reveals me...
ORGANISM(S): Human Hs578t Cells 
2025-02-12 | MSV000097104 | MassIVE
GenomicsChIP-sequencing of Snai1 transcription factor in triple negative breast cancer cell line Hs578T
This experiment is performed to reveal the novel binding sites of Snai1 transcription factor globally in triple negative breast cancer cell line Hs578T. We also reveal the effect of TGF cytokine on the binding sites of Snai1.
ORGANISM(S): Homo sapiens 
2018-04-25 | E-MTAB-5242 | biostudies-arrayexpress
ProteomicsDDA-PASEF and diaPASEF acquired HCC1806/HS578T proteomic datasets with deliberate batch effects
We generated two comprehensive large-scale proteomics datasets with deliberate batch effects using the latest parallel accumulation-serial fragmentation in both Data-Dependent and Data-Indepentdent Acquisition modes. This dataset contain a balanced two-class design (cell lines: HCC1806 vs HS578T), a...
ORGANISM(S): Homo sapiens (Human) 
2023-11-21 | PXD041391 | Pride
Dda Pasef Dia Hcc1806 Hs578t Batch effects 
GenomicsRNA-seq in Hs578T cells stimulated with TGF-β
RNA-seq in Hs578T cells stimulated with TGF-β
PRJNA639269 | ENA
ProteomicsLC-MS/MS from human cell lines PC3, HS578T, MDA-MB-231 and MCF10A
Liquid Chromatography Electrospray Ionization Tandem Mass Spectrometry (LC/ESI-MS/MS) was used in the human cell lines HS578T, MDA-MB-231, MCF10A, and PC3. Label free quantification of protein abundances enabled comparison of the expression levels of talin 1 and talin 2 within each cell line. Mass s...
ORGANISM(S): Homo sapiens (Human) 
2025-01-07 | PXD058465 | Pride
Human 231 Mda-mb Hs578t Pc3 Mcf10a 
TranscriptomicsTranscriptomic profiling of AR knockdown in human triple-negative breast cancer Hs578T cells
This study aimed to investigate transcriptomic alterations induced by androgen receptor (AR) silencing in the radioresistant Hs578T triple-negative breast cancer (TNBC) cells. Using siRNA-mediated knockdown of AR, RNA sequencing was performed to identify genes and pathways associated with AR signali...
ORGANISM(S): Homo sapiens 
2025-11-14 | E-MTAB-16017 | biostudies-arrayexpress
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