Sort   by:  
 Page size 
ProteomicsPIGEON-FEATHER datasets, extracting site-resolved energetic information from HX/MS experiments
We present PIGEON-FEATHER, a method for calculating free energies of opening (∆Gop) at single- or near-single-amino acid resolution for protein ensembles of all sizes from hydrogen exchange/mass spectrometry (HX/MS) data. PIGEON-FEATHER disambiguates and reconstructs all experimentally measured isot...
ORGANISM(S): Escherichia coli 
2024-11-05 | PXD057539 | Pride
Ecdhfr Hdhfr Laci Hx/ms 
ProteomicsPIGEON-FEATHER datasets, extracting site-resolved energetic information from HX/MS experiments
We present PIGEON-FEATHER, a method for calculating free energies of opening (∆Gop) at single- or near-single-amino acid resolution for protein ensembles of all sizes from hydrogen exchange/mass spectrometry (HX/MS) data. PIGEON-FEATHER disambiguates and reconstructs all experimentally measured isot...
ORGANISM(S): Escherichia coli 
2024-08-06 | PXD054550 | Pride
Ecdhfr Hdhfr Laci Hx/ms 
UnknownIn Silico Study Identified Methotrexate Analog as Potential Inhibitor of Drug Resistant Human Dihydrofolate Reductase for Cancer Therapeutics.
Not available
S-EPMC7435474 | biostudies-literature
UnknownDirect NMR observation of a substrate protein bound to the chaperonin GroEL.
Not available
S-EPMC1188259 | biostudies-literature
UnknownSide chain conformational averaging in human dihydrofolate reductase.
Not available
S-EPMC3985697 | biostudies-literature
UnknownStructure-activity correlations for three pyrido[2,3-d]pyrimidine antifolates binding to human and Pneumocystis carinii dihydrofolate reductase.
Not available
S-EPMC4461351 | biostudies-literature
UnknownKinetic and structural analysis for potent antifolate inhibition of Pneumocystis jirovecii, Pneumocystis carinii, and human dihydrofolate reductases and their active-site variants.
Not available
S-EPMC3716164 | biostudies-literature
UnknownIn Silico Study Probes Potential Inhibitors of Human Dihydrofolate Reductase for Cancer Therapeutics.
Not available
S-EPMC6406960 | biostudies-literature
UnknownHuman dihydrofolate reductase influences the sensitivity of the malaria parasite Plasmodium falciparum to ketotifen - A cautionary tale in screening transgenic parasites.
Not available
S-EPMC5050295 | biostudies-literature
UnknownTargeting species specific amino acid residues: Design, synthesis and biological evaluation of 6-substituted pyrrolo[2,3-d]pyrimidines as dihydrofolate reductase inhibitors and potential anti-opportunistic infection agents.
Not available
S-EPMC5967623 | biostudies-literature
Sort   by:  
 Page size