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Hsp90 is a molecular chaperone involved in the regulation and maturation of kinases and transcription factors. In C. elegans Hsp90 participates in the development of fertility, maintenance of muscle structure and the regulation of stress response and dauer state. To understand the consequences of Hs...
ORGANISM(S): Caenorhabditis elegans 
2018-10-17 | PXD006185 | Pride
Sample 1: Control Sample 2: Interaction proteins of Flag-cGAS Sample 3: Interaction proteins of Flag-cGAS with lactate treatment Sample 4: Interaction proteins of Flag-PSMA4 Sample 5: Interaction proteins of Flag-PSMA4 with lactate treatment
ORGANISM(S): Homo sapiens (Human) 
2025-03-21 | PXD053886 | Pride
Covalent modification of DNA distinguishes cellular identities and is crucial for regulating the pluripotency and differentiation of embryonic stem (ES) cells. The recent demonstration that 5-methylcytosine (5-mC) may be further modified to 5-hydroxymethylcytosine (5-hmC) in ES cells has revealed a ...
ORGANISM(S): Homo sapiens 
Aberrant DNA methylation is common in cancer. To associate DNA methylation with gene function, we performed RNAseq upon tumor tissue and matched normal tissues of two ccRCC (clear cell renal cell carcinoma) patients. To quantify 5mC and 5hmC level in each CG site at genome-wide level, we performed ...
ORGANISM(S): Homo sapiens 
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