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ProteomicsYi-xin-shu Capsule Ameliorates Cardiac Hypertrophy by Regulating RB/HDAC1/GATA4 Signaling Pathway in Abdominal Aorta Coarctation-Induced Rat Model
Background: Cardiac hypertrophy (CH) is the main pathological basis of malignant cadiovascular diseases such as chronic heart failure (CHF). Mitigating and preventing CH is the key strategy for the treatment of ventricular remodeling in CHF. Yi-Xin-Shu capsule (YXS) is highly applied in clinical tre...
ORGANISM(S): Rattus Rattus 
2021-05-26 | PXD026267 |
UnknownYiXin-Shu, a ShengMai-San-based traditional Chinese medicine formula, attenuates myocardial ischemia/reperfusion injury by suppressing mitochondrial mediated apoptosis and upregulating liver-X-receptor α.
Not available
S-EPMC4786861 | biostudies-literature
TranscriptomicsProfiling of H3.3
Histone variants can effect nucleosome stability or affect histone of DNA modifications. H3.3 is a major H3 histone variant that is incorporated into chromatin outside of S-phase in various eukaryotes. In animals, H3.3 is associated with active transcription and possibly maintenance of transcription...
ORGANISM(S): Arabidopsis thaliana 
2014-03-10 | E-MTAB-1685 | biostudies-arrayexpress
MetabolomicsAge-, sex- and proximal-distal-resolved multi-omics identifies regulators of intestinal aging in non-human primates.

The incidence of intestinal diseases increases with age, but the regulators of gut aging and the molecules linking gut aging and diseases remain largely unknown. By profiling the transcriptome, proteome, phosphoproteome and metabolome of 104 Macaca fascicularis large intestinal tissues, ...

2023-12-14 | MTBLS7612 | MetaboLights
UnknownVitamin C deficiency induces hypoglycemia and cognitive disorder through S-nitrosylation-mediated activation of glycogen synthase kinase 3β.
Not available
S-EPMC9399387 | biostudies-literature
TranscriptomicsChronic Alcohol Consumption Alters micro-RNA Radiation Responses in the Mouse Liver
Accumulating evidence suggests that lifestyle-related factors may influence radiation responses and the resulting cancer risks through epigenetic mechanisms, such as miRNA regulations. Chronic alcohol consumption is a major risk factor for various pathologies, including alcoholic liver disease. We h...
ORGANISM(S): Mus musculus 
2016-03-15 | E-GEOD-79186 | biostudies-arrayexpress
UnknownChalcone synthase is ubiquitinated and degraded via interactions with a RING-H2 protein in petals of Paeonia 'He Xie'.
Not available
S-EPMC6760318 | biostudies-literature
UnknownErianin against Staphylococcus aureus Infection via Inhibiting Sortase A.
Not available
S-EPMC6215257 | biostudies-literature
UnknownO-GlcNAcylation of TDP-43 suppresses proteinopathies and promotes TDP-43's mRNA splicing activity.
Not available
S-EPMC8183420 | biostudies-literature
UnknownIntegrative omics analysis reveals insights into small colony variants of Staphylococcus aureus induced by sulfamethoxazole-trimethoprim.
Not available
S-EPMC11179224 | biostudies-literature
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