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ProteomicsKH_dKO: Simultaneous loss of skeletal muscle myosin heavy chain IIx and IIb causes severe hypoplasia of skeletal muscles in young mice
Simultaneous loss of skeletal muscle myosin heavy chain IIx and IIb causes severe hypoplasia of skeletal muscles in young mice
ORGANISM(S): Mus Musculus (mouse) 
2022-11-28 | PXD032244 | JPOST Repository
TranscriptomicsEarly and late response of Nematostella vectensis transcriptome to heavy metals
Environmental contamination from heavy metals poses a global concern for the marine environment, as heavy metals are passed up the food chain and persist in the environment long after the pollution source is contained. Cnidarians, dating back to 700 million years ago, play an important role in shapi...
ORGANISM(S): Nematostella vectensis 
2015-12-22 | E-GEOD-58769 | biostudies-arrayexpress
GenomicsPaired antibody heavy-light chain sequencing
Paired antibody heavy-light chain sequencing
PRJEB25901 | ENA
TranscriptomicsAllele specific analysis of the immunoglobulin heavy chain locus by simultaneous analysis of the productive and the non-productive allele through paired-end 4C sequencing analysis in mature B cells
In developing B cells the immunoglobulin heavy chain (IgH) locus is thought to move from repressive to permissive chromatin compartments to facilitate its scheduled rearrangement. In mature B cells, maintenance of allelic exclusion has been proposed to involve recruitment of the non-productive IgH a...
ORGANISM(S): Mus musculus 
2013-06-01 | E-GEOD-47128 | biostudies-arrayexpress
TranscriptomicsTargeted chromatin profiling reveals novel enhancers in Ig heavy and light chain loci.
Chip-chip from pro-B cells from Rag1KO mice for H3K27ac and RNA Pol II Identification of novel enhancers from Ig heavy and light chain loci Rag1KO pro-B epigenetic landscape at Ig heavy and light chain loci
ORGANISM(S): Mus musculus 
2014-01-03 | E-GEOD-53766 | biostudies-arrayexpress
TranscriptomicsAllele specific analysis of the immunoglobulin heavy chain locus
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Mus musculus 
2013-06-01 | E-GEOD-47129 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of yeast expressing mouse major histocompatibility complex class I heavy chain H-2K(b)
To dissect the requirements of membrane protein degradation from the ER, we expressed the mouse major histocompatibility complex class I heavy chain H-2K(b) in yeast. Like other proteins degraded from the ER, unassembled H-2K(b) heavy chains are not transported to the Golgi but are degraded in a pro...
ORGANISM(S): Saccharomyces cerevisiae 
2005-06-28 | E-SMDB-1576 | biostudies-arrayexpress
ProteomicsValidation of the expression of clathrin heavy chain muscle isoform including exon 31 at the protein level
A single exon alternative splicing in the CLTC gene determines clathrin coat organization. This event controls plasticity from clathrin-coated pits to plaques, structures that are essential for muscle fiber function and maintenance
ORGANISM(S): Homo sapiens (Human) 
2020-06-19 | PXD018333 | Pride
Human Cltc exon 31 Clathrin heavy chain Differentiation Alternative splicing Clathrin plaques Clathrin coated-pits Muscle 
GenomicsHeavy chain immunoglobulin sequencing of Lyme disease PBMCs
Heavy chain immunoglobulin sequencing of Lyme disease PBMCs
PRJNA454501 | ENA
MetabolomicsIn plaque-mass spectrometry imaging of a bloom-forming alga during viral infection reveals a metabolic shift towards odd-chain fatty acid lipids (Imaging MS assays)

Tapping into the metabolic cross-talk between a host and its virus can reveal unique strategies employed during infection. Viral infection is a dynamic process that generates an evolving metabolic landscape. Gaining a continuous view into the infection process is highly challenging and is limited...

2018-11-29 | MTBLS769 | MetaboLights
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