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TranscriptomicsEarly and late response of Nematostella vectensis transcriptome to heavy metals
Environmental contamination from heavy metals poses a global concern for the marine environment, as heavy metals are passed up the food chain and persist in the environment long after the pollution source is contained. Cnidarians, dating back to 700 million years ago, play an important role in shapi...
ORGANISM(S): Nematostella vectensis 
2015-12-22 | E-GEOD-58769 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human HepG2 cells exposed to 2,3-Dimethoxy-1,4-naphthoquinone (DMNQ), N-nitrosodimethylamine (DMN), phenol and six heavy metals
From the results of gene expression analyses of HepG2 under the exposure of 2,3-Dimethoxy-1,4-naphthoquinone (DMNQ), N-nitrosodimethylamine (DMN), phenol and six heavy metals We showed that biological action of six heavy metals were clearly related to that of DMNQ and distinguishable from the other ...
ORGANISM(S): Homo sapiens 
2009-04-08 | E-GEOD-6907 | biostudies-arrayexpress
TranscriptomicsMycobacterial p(1)-type ATPases mediate resistance to zinc poisoning in human macrophages.
Mycobacterium tuberculosis thrives within macrophages by residing in phagosomes and preventing them from maturing and fusing with lysosomes. A parallel transcriptional survey of intracellular mycobacteria and their host macrophages revealed signatures of heavy metal poisoning. In particular, mycobac...
ORGANISM(S): Mycobacterium tuberculosis 
2012-01-27 | E-BUGS-122 | biostudies-arrayexpress
TranscriptomicsMicroarray-based Analysis of Gene Expression in Lycopersicon esculentum Roots in Response to Cadmium, Chromium, Mercury and Lead
We hypothesize that microarray-based analysis of Lycopersicon esculentum is a sensitive tool for the early detection of potential toxicity of heavy metals, as well as an effective tool for identifying the heavy metal-specific genes. To test the hypothesis, the Agilent whole-genome cDNA microarrays w...
ORGANISM(S): Solanum lycopersicum 
2014-11-06 | E-GEOD-63024 | biostudies-arrayexpress
TranscriptomicsGenome-wide transcriptional profiling of C. elegans in a heavy metal contaminated soil after nZVI treatment
Classical ecotoxicological test and high-throughput molecular tools (microarray) were conducted on C. elegans to assess the effectiveness and ecosafety of a nanoremediation strategy applied to a highly polluted soil environment with heavy metals (HMs). We stablished a profiled gene expression in C. ...
ORGANISM(S): Caenorhabditis elegans 
2022-01-24 | GSE145995 | GEO
ProteomicsComparison of arsenite and cadmium: Metal homeostasis and cellular stress response in human bronchial cells
Human exposure to cadmium and inorganic arsenic persists despite declining environmental levels. A proteomic profiling with label-free quantification was used to characterize the most abundant changes in protein expression after arsenite and cadmium exposure in human bronchial epithelial cells (BEAS...
ORGANISM(S): Homo sapiens (Human) 
2026-09-21 | PXD076643 | Pride
Human Lc-ms Lung Heavy metal toxicity Oxidative stress Cells 
Genomics
soil heavy metal remediation
PRJNA1066996 | ENA
GenomicsGenome-wide transcriptional profiling of C. elegans in a heavy metal contaminated soil after nZVI treatment
Genome-wide transcriptional profiling of C. elegans in a heavy metal contaminated soil after nZVI treatment
PRJNA608936 | ENA
TranscriptomicsGene expression profiling as a tool for sediment risk assessment: a pilot study using Caenorhabditis elegans whole genome microarrays
Toxicity of river sediments are assessed using whole sediment toxicity tests with benthic organisms. The challenge, however, is the differentiation between multiple effects caused by complex contaminant mixtures and the unspecific toxicity endpoints such as survival, growth or reproduction. Moreover...
ORGANISM(S): Caenorhabditis elegans 
2008-06-25 | E-GEOD-11837 | biostudies-arrayexpress
Genomics
Soil heavy metal remediation and stabilization
PRJNA1067070 | ENA
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