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ModelsStavrum2013 - Tryptophan Metabolism in Liver
Stavrum2013 - Tryptophan Metabolism in Liver This model is described in the article: Model of tryptophan metabolism, readily scalable using tissue-specific gene expression data. Stavrum AK, Heiland I, Schuster S, Puntervoll P, Ziegler M. J. Biol. Chem. 2013 Nov; 288(48): ...
2024-09-02 | BIOMD0000000602 | BioModels
ModelsHeiland2019 - NAD pathway model analysing the impact of NNMT on pathway dynamics and evolution
This is a detailed model of NAD biosynthesis and consumption representing pathway variances across kingdoms.
2019-07-26 | MODEL1905220001 | BioModels
ModelsHeiland2019 - Two compartment model of NAD biosynthesis and consumption
The model is based on MODEL1905220001 but has two compartments that have different composition of the biosynthetic enzymes NADA and NamPT. One compartment contains in addition NNMT, the other one does not. Both compartments are competing for a common Nam source.
2019-08-01 | MODEL1905220002 | BioModels
TranscriptomicsDeep sequencing of endogenous mRNA from Caenorhabditis elegans in the presence and absence of 1-methylnicotinamide (MNA) and nicotinic acid (NA)
Sirtuins, a family of histone deacetylases, have a fiercely debated role in regulating lifespan of different species. Contrasting recent observations, we here find that overexpression of sir-2.1, the orthologue of mammalian SirT1, does extend C. elegans lifespan. Sirtuins are known to convert NAD+ i...
ORGANISM(S): Caenorhabditis elegans 
2013-08-09 | E-GEOD-49662 | biostudies-arrayexpress
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