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TranscriptomicsTranscription profiling of mouse ES cell derived brachyury+ (T) cell specific transcriptome
This experiment is part of the FunGenES project (FunGenES - Functional Genomics in Embryonic Stem Cells partially funded by the 6th Framework Programme of the European Union, http://www.fungenes.org). The experiment was conducted at University of Cologne, Cologne, Germany. Goal of the experiment was...
ORGANISM(S): Mus musculus 
2010-05-12 | E-TABM-716 | biostudies-arrayexpress
TranscriptomicsHiC-sequencing in human monocyte differentiation (3D-MO)
This dataset consists of in situ HiC-seq data from human monocytes, monocyte-derived dendritic cells as well as monocyte-derived cells that were subjected to siRNA treatment targeting CTCF or RAD21. In total, the data set includes 42 samples.
ORGANISM(S): Homo sapiens 
2022-06-24 | E-MTAB-10848 | biostudies-arrayexpress
TranscriptomicsA compendium of antibiotic-induced transcription profiles reveals broad regulation of P. multocida virulence genes
Treatment of bacteria with antibiotics at or close to the inhibitory concentration leads to specific transcriptional responses often affecting target genes and targets pathways. A dataset of transcriptional profiles (compendium) induced by antibiotics with known mode-of-action (MoA) can be used to g...
ORGANISM(S): Pasteurella multocida 
2008-06-01 | E-GEOD-10051 | biostudies-arrayexpress
TranscriptomicsCynomolgus macaque model of H7N9 influenza infection
The objective of this study is to characterize the response to newly emerged, highly pathogenic H7N9 influenza virus isolated from human patients in 2013 in China. This study examines the pathogenesis of H7N9 influenza in cynomolgus macaques. The study compares lung lesions to adjacent right lowe...
ORGANISM(S): Macaca fascicularis 
2014-07-22 | E-GEOD-48976 | biostudies-arrayexpress
TranscriptomicsThe transcriptional response of Cryptococcus neoformans to ingestion by Acanthamoeba castellanii and murine macrophages
Virulence of Cryptococcus neoformans for mammals was proposed to emerge from evolutionary pressures on its natural environment by protozoan predators, which selected for strategies that allow survival within macrophages. In fact, Acanthamoeba castellanii ingests yeast cells, which then replicate int...
ORGANISM(S): Cryptococcus neoformans 
2013-03-14 | E-GEOD-45027 | biostudies-arrayexpress
TranscriptomicsComparative transcriptomic analysis of acute host responses during 2009 pandemic H1N1 influenza infection in mouse, macaque, and swine (swine dataset)
Background: The 2009 pandemic H1N1 influenza virus emerged in swine and quickly became a major global health threat. In mouse, non-human primate, and swine infection models, the pH1N1 virus efficiently replicates in the lung and induces pro-inflammatory host responses; however, whether similar or di...
ORGANISM(S): Sus scrofa 
2012-09-12 | E-GEOD-40847 | biostudies-arrayexpress
TranscriptomicsComparative transcriptomic analysis of acute host responses during 2009 pandemic H1N1 influenza infection in mouse, macaque, and swine (mouse dataset)
Background: The 2009 pandemic H1N1 influenza virus emerged in swine and quickly became a major global health threat. In mouse, non-human primate, and swine infection models, the pH1N1 virus efficiently replicates in the lung and induces pro-inflammatory host responses; however, whether similar or di...
ORGANISM(S): Mus musculus 
2012-08-13 | E-GEOD-40091 | biostudies-arrayexpress
TranscriptomicsComparative Pathogenesis of Three Human and Zoonotic SARS-CoV Strains in Cynomolgus Macaques
The severe acute respiratory syndrome (SARS) epidemic was characterized by increased pathogenicity in the elderly due to an early exacerbated innate host response. SARS-CoV is a zoonotic pathogen that entered the human population through an intermediate host like the palm civet. To prevent future in...
ORGANISM(S): Macaca mulatta 
2011-08-31 | E-GEOD-23955 | biostudies-arrayexpress
UnknownAlcohol Consumption and Risk of Coronary Artery Disease (from the Million Veteran Program).
Not available
S-EPMC6734183 | biostudies-literature
UnknownGenetic architecture of subcortical brain structures in 38,851 individuals.
Not available
S-EPMC7055269 | biostudies-literature
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