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TranscriptomicscaArray_dobbi-00100: Interlaboratory comparability study of cancer gene expression analysis using oligonucleotide microarrays
A key step in bringing gene expression data into clinical practice is the conduct of large studies to confirm preliminary models. The performance of such confirmatory studies and the transition to clinical practice requires that microarray data from different laboratories are comparable and reproduc...
ORGANISM(S): Homo sapiens 
2015-05-07 | E-GEOD-68606 | biostudies-arrayexpress
TranscriptomicscaArray_jacks-00113: Murine KRASLA lung cancer gene expression
Tumors from 5-6 month old KrasLA mice were dissected. Gene expression analysis on U74A affy chips. 19 normal lungs from age matched controls were also includeed **NOTE: Migrated from caArray 1.x, identifier='gov.nih.nci.ncicb.caarray:Experiment:1015897590231167:1' jacks-00113 Assay Type: Gene Expres...
ORGANISM(S): Mus musculus 
2015-06-26 | E-GEOD-70271 | biostudies-arrayexpress
TranscriptomicscaArray_notte-00422: Molecular Dissection of Colon Cancer
RNA expression data was generated as part of a colon cancer study. Samples were obtained from patients, including primary colon cancer, polyps, metastases, and matched normal mucosa (obtained from the margins of the resection). The RNA was extracted from tissue samples obtained from resections and h...
ORGANISM(S): Homo sapiens 
2015-05-02 | E-GEOD-68468 | biostudies-arrayexpress
TranscriptomicscaArray_jacob-00182: Gene expression-based survival prediction in lung adenocarcinoma: a multi-site, blinded validation study
Here we report a large, training*testing, multi-site, blinded validation study to characterize the performance of several prognostic models based on gene expression for 442 lung adenocarcinomas. The hypotheses proposed examined whether microarray measurements of gene expression either alone or combi...
ORGANISM(S): Homo sapiens 
2015-05-02 | E-GEOD-68465 | biostudies-arrayexpress
TranscriptomicscaArray_willm-00140: TARGET-ALL Expression: Children's Oncology Group Study 9906 for High-Risk Pediatric ALL
Gene Expression Classifiers for Minimal Residual Disease and Relapse Free Survival Improve Outcome Prediction and Risk Classification in Children with High Risk Acute Lymphoblastic Leukemia: A Children's Oncology Group Study willm-00140 Assay Type: Gene Expression Provider: Affymetrix Array Designs:...
ORGANISM(S): Homo sapiens 
2015-05-12 | E-GEOD-68735 | biostudies-arrayexpress
TranscriptomicscaArray_hanas-00078: Distinctive molecular profiles of high-grade and low-grade gliomas based on oligonucleotide microarray analysis
Astrocytomas are heterogeneous intracranial glial neoplasms ranging from the highly aggressive malignant glioblastoma multiforme (GBM) to the indolent, low-grade pilocytic astrocytoma. We have investigated whether DNA microarrays can identify gene expression differences between high-grade and low-gr...
ORGANISM(S): Homo sapiens 
2015-06-25 | E-GEOD-70231 | biostudies-arrayexpress
TranscriptomicscaArray_becic-00235: Gene expression alterations in prostate cancer predicting tumor aggression and preceding development of malignancy
The incidence of prostate cancer is frequent, occurring in almost one-third of men older than 45 years. Only a fraction of the cases reach the stages displaying clinical significance. Despite the advances in our understanding of prostate carcinogenesis and disease progression, our knowledge of this ...
ORGANISM(S): Homo sapiens 
2015-05-06 | E-GEOD-68555 | biostudies-arrayexpress
TranscriptomicscaArray_green-00155: Global expression profiling identifies signatures of tumor virulence in MMTV-PyMT-transgenic mice
Comparison the gene expression profiles of mouse mammary tumors derived from MMTV-PyMT transgenic in five different strains including FVB/NJ, I/LnJ F1, NZB/B1NJ F1, MOLF/Ei F1 and LP/J F1 and identification of signatures of tumor virulence. **NOTE: Migrated from caArray 1.x, identifier='gov.nih.nci....
ORGANISM(S): Mus musculus 
2015-06-20 | E-GEOD-70052 | biostudies-arrayexpress
TranscriptomicscaArray_golub-00095: Diffuse large B-cell lymphoma outcome prediction
Diffuse large B-cell lymphoma (DLBCL), the most common lymphoid malignancy in adults, is curable in less than 50% of patients. Prognostic models based on pre-treatment characteristics, such as the International Prognostic Index (IPI), are currently used to predict outcome in DLBCL. However, clinical...
ORGANISM(S): Homo sapiens 
2015-05-15 | E-GEOD-68895 | biostudies-arrayexpress
TranscriptomicscaArray_golub-00460: Prediction of central nervous system embryonal tumour outcome based on gene expression
Embryonal tumours of the central nervous system (CNS) represent a heterogeneous group of tumours about which little is known biologically, and whose diagnosis, on the basis of morphologic appearance alone, is controversial. Medulloblastomas, for example, are the most common malignant brain tumour of...
ORGANISM(S): Homo sapiens 
2015-05-16 | E-GEOD-68956 | biostudies-arrayexpress
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