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ProteomicsHunting for Hemopexin Receptors: One Saga
Maintaining hemopexin (HPX) plasma levels protects against heme-activated inflammation and the toxicity of heme and its iron during hemolysis. Plasma heme regulates HPX turnover in hepatocytes, thus changing plasma HPX. However, the cell biology of hepatic HPX-mediated heme delivery is not fully elu...
ORGANISM(S): Homo sapiens (Human) 
2025-12-22 | PXD060789 | Pride
Receptor Hemostasis Low density lipoprotein receptor Human Hemopexin Transferrin receptor 1 Hemolysis Human hepatocytes 
TranscriptomicsMicroarray identification of functional modules involving Haptoglobin and/or Hemopexin
Haptoglobin and Hemopexin are plasma acute phase proteins that bind with high affinity hemoglobin and heme, respectively. Several studies have demonstrated that they have a key role in the protection against oxidative stress and inflammation. However, little is known about the functional modules in ...
ORGANISM(S): Mus musculus 
2006-11-01 | GSE3656 | GEO
TranscriptomicsMicroarray identification of functional modules involving Haptoglobin and/or Hemopexin
Haptoglobin and Hemopexin are plasma acute phase proteins that bind with high affinity hemoglobin and heme, respectively. Several studies have demonstrated that they have a key role in the protection against oxidative stress and inflammation. However, little is known about the functional modules in ...
ORGANISM(S): Mus musculus 
2006-10-31 | E-GEOD-3656 | biostudies-arrayexpress
GenomicsSpatial transcriptome analysis defines heme as a hemopexin-targetable inflammatoxin in the brain
Spatial transcriptome analysis defines heme as a hemopexin-targetable inflammatoxin in the brain
PRJNA754793 | ENA
GenomicsHaptoglobin and Hemopexin Redirect Heme-Driven Oxidative Stress and Neurotoxicity in Organotypic Brain Slices
Haptoglobin and Hemopexin Redirect Heme-Driven Oxidative Stress and Neurotoxicity in Organotypic Brain Slices
PRJNA1273729 | ENA
UnknownHemopexin as an Inhibitor of Hemolysis-Induced Complement Activation.
Not available
S-EPMC7412979 | biostudies-literature
UnknownHemopexin deficiency promotes acute kidney injury in sickle cell disease.
Not available
S-EPMC7218735 | biostudies-literature
UnknownAn alternative view of the proposed alternative activities of hemopexin.
Not available
S-EPMC3125864 | biostudies-literature
UnknownHemopexin induces nephrin-dependent reorganization of the actin cytoskeleton in podocytes.
Not available
S-EPMC2573012 | biostudies-literature
UnknownIdentification of oxidative modifications of hemopexin and their predicted physiological relevance.
Not available
S-EPMC5566522 | biostudies-literature
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