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ProteomicsDiscovery and mechanistic studies of cytotoxic cyclotides from the medicinal herb Hybanthus enneaspermus (Linn) F. Muell
Cyclotides are a family of plant-derived peptides characterized by a ~30 amino acid cyclic backbone and a cystine knot motif. Cyclotides have diverse bioactivities, and in particular their cytotoxicity has attracted significant attention for its potential anti-cancer applications. Hybanthus enneaspe...
ORGANISM(S): Hybanthus enneaspermus 
2020-05-13 | PXD017924 | Pride
Anticancer property Surface plasmon resonance (spr) Peptide chemical synthesis Peptide-membrane interaction Nuclear magnetic resonance (nmr) Cyclotide Cancer cell cytotoxicity 
ModelsMacNamara2012 - Signal transduction
MacNamara2012 - Signal transduction A toy model of signal tranduction to illustrate how different logic formalizms (Boolean, fuzzy logic and differential equations) treat state and time, is described here. This model was generated from the PKN-ToyPB.sif file available in...
2005-01-01 | MODEL1305240000 | BioModels
TranscriptomicsStable pausing by RNA polymerase II provides an opportunity to target and integrate regulatory signals
Metazoan gene expression is often regulated after the recruitment of RNA polymerase II (Pol II) to promoters, through the controlled release of promoter-proximally paused Pol II into productive RNA synthesis. Despite the prevalence of paused Pol II, very little is known about the dynamics of these e...
ORGANISM(S): Drosophila melanogaster 
2013-10-31 | E-GEOD-49078 | biostudies-arrayexpress
UnknownOncogenic CDK13 mutations impede nuclear RNA surveillance.
Not available
S-EPMC10184553 | biostudies-literature
UnknownParacrine orchestration of intestinal tumorigenesis by a mesenchymal niche.
Not available
S-EPMC7490650 | biostudies-literature
UnknownIntraperitoneal drain placement and outcomes after elective colorectal surgery: international matched, prospective, cohort study.
Not available
S-EPMC10364732 | biostudies-literature
UnknownGlobal anaesthesia practice using inguinal hernia surgery as a tracer condition: a secondary analysis of an international prospective cohort study.
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S-EPMC12519944 | biostudies-literature
UnknownA prognostic model for use before elective surgery to estimate the risk of postoperative pulmonary complications (GSU-Pulmonary Score): a development and validation study in three international cohorts.
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S-EPMC12056793 | biostudies-literature
UnknownSARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study.
Not available
S-EPMC7995808 | biostudies-literature
UnknownExtended pharmacological thromboprophylaxis and clinically relevant venous thromboembolism after major abdominal and pelvic surgery: international, prospective, propensity score-weighted cohort study.
Not available
S-EPMC11894929 | biostudies-literature
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