Cyclotides are a family of plant-derived peptides characterized by a ~30 amino acid cyclic backbone and a cystine knot motif. Cyclotides have diverse bioactivities, and in particular their cytotoxicity has attracted significant attention for its potential anti-cancer applications. Hybanthus enneaspe...
Cyclotides are circular and cystine-rich peptides which are little amenable to chemical modifications for probe design in chemical biology. The cyclotide [T20K]kalata B1 is an immune system modulating drug reported for its therapeutic application in multiple sclerosis.
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human)