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Cyclotides are a family of plant-derived peptides characterized by a ~30 amino acid cyclic backbone and a cystine knot motif. Cyclotides have diverse bioactivities, and in particular their cytotoxicity has attracted significant attention for its potential anti-cancer applications. Hybanthus enneaspe...
ORGANISM(S): Hybanthus enneaspermus 
2020-05-13 | PXD017924 | Pride
Genomics
Transcriptome sequencing of Viola odorata for cyclotide discovery
Cyclotides are circular and cystine-rich peptides which are little amenable to chemical modifications for probe design in chemical biology. The cyclotide [T20K]kalata B1 is an immune system modulating drug reported for its therapeutic application in multiple sclerosis.
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) 
2017-09-26 | PXD004798 | Pride
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