Clustered regularly interspaced short palindromic repeat (CRISPR) RNA-guided nucleases have gathered considerable excitement as a tool for genome engineering. However, questions remain about the specificity of their target site recognition. Most previous studies have examined predicted off-target bi...
In plants, multiple lineages have evolved sex chromosomes independently, providing a powerful comparative framework, but few specific determinants controlling the expression of a specific sex have been identified. We investigated sex-determinants in Caucasian persimmon, Diospyros lotus, a dioecious ...
Hybridization of diverged taxa often result in lethality or sterility. We previously described natural variation for postzygotic incompatibility in the cross of diploid Arabidopsis thaliana to Arabidopsis arenosa. Hybrid seed death in this system has a complex genetic basis, involving many non-addit...
The study incorporated 5 keloid disease (KD) and 5 normal skin (NS) samples, and due to challenges in obtaining primary samples, we had a sample size of 3 biological replicates for FKN, 3 for DFSP made up of 2 primary cells and 1 cell line, and 2 Fibrosarcoma cell lines FS-CL-1 (HT-1080 [HT1080], C...
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Isoform switching facilitates period control in the Neurospora crassa circadian clock.
Akman OE, Locke JC, Tang S, Carré I, Millar AJ, Rand DA Mol. Syst. Biol.
2008;Vol 4: 164 18277380
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