Hepatoma cell line

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Repository

biostudies-arrayexpress (246)
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Tissue

Hepatocyte (11)
Cell culture (8)
Liver (6)
Hepatoma cell line (4)
Plasma Non-glyco (2)
Permanent cell line cell (2)
SNU-475 cell (2)
Embryonic stem cell (1)
Liver cancer cell (1)
Malignant cell (1)
Neural progenitor cell (1)
Regulation of hepatocyte differentiation (1)
Stem cell (1)

Disease

Liver cancer (2)
Not Available (2)
Hepatocellular carcinoma (2)
Hepatocellular carcinoma-non tumorous region (1)
Cancer cell line pool (1)
Normal (1)
Disease free (1)
Liver carcinoma (1)
Type 2 diabetes mellitus (1)

Technology Type

Mass Spectrometry (23)
Shotgun proteomics (10)
Mass spectrometry (7)
Bottom-up proteomics (7)
Affinity purification coupled with mass spectrometry proteomics (5)
Data-dependent acquisition (5)
Illumina HiSeq 2000 (3)
NMR spectroscopy (3)
Mass spectrometry assay (2)
Data-independent acquisition (2)
Gel-based experiment (2)
Illumina HiSeq 2000, ILLUMINA, Illumina HiSeq 4000 (1)
HiSeq X Ten (ILLUMINA), HiSeq X Ten, ILLUMINA (1)
Illumina HiSeq 2500 (ILLUMINA) (1)
HiSeq X Ten (1)
ILLUMINA, Illumina HiSeq 2000 (1)
Illumina 1.2M, Affymetrix 6.0, Affymetrix 6.0 - CHIAMO (1)
Illumina Genome Analyzer II, Illumina HiSeq 2000 (1)
DiaPASEF (1)
SRM/MRM (1)
Top-down proteomics (1)

Instrument Platform

Illumina HiSeq 2500 (14)
Illumina NovaSeq 6000 (4)
NextSeq 550 (3)
Illumina HiSeq 2000 (3)
MS:1000031 (3)
Q Exactive (3)
TripleTOF 5600 (3)
Liquid Chromatography MS - positive - reverse phase (3)
Liquid Chromatography MS - negative - reverse phase (3)
Illumina NovaSeq X (2)
Instrument (2)
LTQ Orbitrap Elite (2)
Orbitrap Fusion (2)
Orbitrap Fusion Lumos (2)
Illumina bead array Reader confocal scanner (1)
NA (1)
NextSeq 500 (1)
LTQ XL ETD (1)
MicrOTOF-Q II (1)
Orbitrap Fusion ETD (1)
Q Exactive HF-X (1)
TripleTOF 6600 (1)
Agilent GC/MS, LECO GC/TOFMS (1)
MS Imaging - positive - direct infusion (1)
5975C Series GC/MSD (Agilent) (1)
Nuclear Magnetic Resonance (NMR) (1)
Liquid Chromatography MS - (1)
Bruker (1)
MS Imaging - (1)
Gas Chromatography MS - positive (1)

Publication Date

2013 (46)
2011 (45)
2015 (33)
2016 (27)
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2012 (26)
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2014 (16)
2026 (10)
2018 (10)
2009 (10)
2022 (9)
2008 (9)
2021 (8)
2020 (8)
2017 (8)
2023 (7)
2019 (6)
2007 (6)
2005 (1)
2006 (1)
2004 (1)
2003 (1)

UNIPROT ID/AC

A0A024RC46 (2)
A0A0B4J220 (2)
A5A3E0 (2)
A6NCN2 (2)
A6NNZ2 (2)
B3KML9 (2)
B3KT93 (2)
B4DRV9 (2)
B4E3A4 (2)
C9JM50 (2)
C9JRZ8 (2)
C9JZR2 (2)
E7EX29 (2)
E9PB61 (2)
E9PKG0 (2)
E9PRG8 (2)
G5E972 (2)
G8JLB6 (2)
H0Y5B0 (2)
H0Y804 (2)
H0YAR2 (2)
P14316 (1)
Q00978 (1)
P52630 (1)
Q9UMW8 (1)
P01562 (1)
O15524 (1)
P17181 (1)
O14543 (1)
P42224 (1)

ENSEMBL ID

ENSG00000170477 (2)
ENSG00000247315 (1)

CHEBI ID

CHEBI:15428 (4)
CHEBI:17191 (4)
CHEBI:30769 (4)
CHEBI:16857 (3)
CHEBI:16977 (3)
CHEBI:16027 (3)
CHEBI:16414 (3)
CHEBI:15354 (3)
CHEBI:15603 (3)
CHEBI:17368 (3)
CHEBI:17790 (2)
CHEBI:18237 (2)
CHEBI:17203 (2)
CHEBI:17196 (2)
CHEBI:30751 (2)
CHEBI:17822 (2)
CHEBI:27266 (2)
CHEBI:28044 (2)
CHEBI:64489 (2)
CHEBI:15366 (2)
CHEBI:16856 (2)
CHEBI:73004 (2)
CHEBI:25017 (2)
CHEBI:15891 (2)
CHEBI:18132 (2)
CHEBI:18186 (2)
CHEBI:15422 (2)
CHEBI:18012 (2)
CHEBI:28842 (2)
CHEBI:16196 (2)

Metabolite Name

L-isoleucine (4)
Glycine (4)
Citric acid (3)
L-valine (3)
L-threonine (3)
L-leucine (3)
L-alanine (3)
UDPglucose (2)
D-Glucose 1-phosphate (2)
Tridecanoic acid (2)
Glutamic acid (2)
PE(16:0/0:0) (2)
Methanol (2)
Valine (2)
Taurine (2)
Serine (2)
L-proline (2)
Hypoxanthine (2)
Creatinine (2)
Creatine (2)
Choline (2)
L-asparagine (2)
Tyrosine (2)
Phenylalanine (2)
Tryptophan (2)
ADP (2)
NADP (2)
NADPH (2)
Benzoic acid (2)
Taurine (2)

First Public Date

2014 (28)
2024 (12)
2025 (7)
2019 (7)
2018 (7)
2026 (6)
2023 (6)
2020 (5)
2017 (4)
2016 (2)
2022 (1)
2015 (1)

Modelling Approach

Ordinary differential equation model (1)

Lab affiliation

University of Vienna, Faculty of Chemistry, Department of Analytical Chemistry (2)
CIRI, Centre International de Recherche en Infectiologie, Team Viral Infection, Metabolism and Immunity, Univ Lyon, Inserm, U1111, CNRS, UMR5308, Université Claude Bernard Lyon 1, Ecole Normale Supérieure de Lyon, 69007, Lyon, France (1)
Department of Biological Engineering, Koch Institute of Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA (1)
Department of Liver Surgery and Transplantation, Liver Cancer Institute and Zhongshan Hospital, Fudan University, Shanghai, China (1)
Department of MS Proteomics at Novo Nordisk A/S in Maaloev, Denmark (1)
Department of Pathology, Medical University of Graz, 8010 Graz, Austria Institute of Chemical Technologies and Analytics, Technische Universität Wien, 1060 Vienna, Austria (1)
Department of Veterinary Biosciences, Melbourne Veterinary School, Faculty of Science, The University of Melbourne, Victoria, Australia (1)
Dept. Medical Microbiology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, the Netherlands (1)
Division of Pharmacotherapy and Experimental Therapeutics, UNC Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, North Carolina, USA (1)
Functional Proteomics Lab, Life Sciences Department, University of Siena, Italy (1)
Institute of Biochemistry of Vilnius University, Vilnius, Lithuania (1)
Key Laboratory of Medical Molecular Virology (MOE/MOH) and Institutes of Biomedical Sciences, Shanghai Medical College, Fudan University (1)
Kyung Hee University (1)
Laboratoire de Spectrométrie de Masse BioOrganique, Analytical Science department, IPHC, CNRS, Strasbourg University, UMR7178, Strasbourg, France (1)
Max Planck Institute for Biochemistry (1)
Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Denmark (1)
Professor of Biochemistry, Adjunct & Emerita Faculty N.T. Veatch Awardee for Distinguished Research & Creativity UMKC School of Science& Engineering, Biological & Biomedical Systems, Kansas City, MO, USA (1)
Protein Research Group Department of Biochemistry and Molecular Biology, University of Southern Denmark, Campusvej 55, 5230 Odense M, Denmark (1)
Research and Diagnostic Institute of Pathology, Medical University of Graz, Stiftingtalstrasse 6, 8010 Graz, Austria; Faculty of Technical Chemistry, Institute of Chemical Technologies and Analytics, Technische Universität Wien, Getreidemarkt 9/164, 1060 Vienna, Austria (1)
Translational Biomedical Proteomics Laboratory, Institute of Molecular and Cell Biology, A*STAR, Singapore 138673, Singapore (1)
Unit of Proteomics- Centro Cardiologico Monzino IRCCS (1)
University College London, Institute of Structural and Molecular Biology, Darwin Building Room 101A, London, WC1E 6BT, United Kingdom (1)

IsPrivate

False (1)

Study type

Transcription profiling by array (170)
RNA-seq of coding RNA (28)
Comparative genomic hybridization by array (7)
ChIP-seq (6)
Methylation profiling by array (6)
RNA-seq of total RNA (5)
RNA-seq of non coding RNA (5)
ChIP-chip by tiling array (3)
Other (3)
Methylation profiling by high throughput sequencing (3)
Unknown experiment type (2)
Transcription profiling by SAGE (1)
Plant - High-throughput sequencing (1)
High-throughput sequencing (1)
Cell line - High-throughput sequencing (1)
Genotyping by array (1)
RIP-seq (1)
MicroRNA profiling by array (1)

Release Date

2013 (54)
2011 (50)
2016 (46)
2015 (42)
2022 (39)
2021 (36)
2014 (36)
2018 (35)
2012 (34)
2020 (32)
2019 (31)
2010 (31)
2024 (30)
2017 (26)
2023 (25)
2008 (22)
2025 (21)
2009 (16)
2007 (10)
2006 (7)
2004 (7)
2005 (6)
2002 (6)
2026 (5)
2003 (4)
2001 (1)
2000 (1)
1999 (1)
1997 (1)
1993 (1)

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Exploring the Effects and Mechanisms of Curcumin on Proliferation, Apoptosis, and Oxidative Stress in Hepatoblastoma cell line via the TLR4/TRAF6/MAPKs Pathway

A combination of bioinformatics and network pharmacology was used to screen curcumin's target genes and related signaling pathways in treating hepatocellular carcinoma. Curcumin-Containing Serum（CUR） was prepared. Cisplatin(CDDP) served as the positive control .The CCK-8 assay, scratch assay, and...

2025-11-28 | MTBLS13412 | MetaboLights

Human Hepatocyte Proteome

Here we report a comprehensive proteomic analysis of purified human hepatocytes and a human hepatoma cell line HepG2. The complete dataset comprises 9,400 proteins and provides quantitative depiction of the proteomes of hepatocytes and HepG2 cells at the protein titer and copy number dimensions.

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

2016-03-07 | MSV000079562 | MassIVE

Preparation of tirapazamine-resistant hepatoma cell line

The aim of the project was to obtain murine hepatoma MH22a [1] cell subline, resistant to anticancer agent 3-amino-1,2,4-benzotriazine-1,4-dioxide (tirapazamine, TPZ), and examine the changes of the protein expression as compared with parental cells, with the main emphasis on the changes of redox pr...

ORGANISM(S): Mus musculus (Mouse)

2023-05-10 | PXD039876 | Pride

Expression profiling of hypoxic HepG2 hepatoma, U87 glioma, and MDA-MB231 breast cancer cells: time course

Analysis of expression changes of cultured HepG2 hepatoma, U87 glioma, and MDA-MB231 breast cancer cells subjected to hypoxia (0.5% O2) for 0, 4, 8, 12 hours . Results provide insight to cell type-specific response to hypoxia. HepG2 hepatoma, U87 glioma, and MDA-MB231 breast cancer cells were collec...

ORGANISM(S): Homo sapiens

2010-06-21 | E-GEOD-18494 | biostudies-arrayexpress

Mechanistic evaluation of the insulin response in H4IIE hepatoma cells: New endpoints for toxicity testing?

Transcriptional profiling of insulin exposed H4IIE cells at different time points (6h-24h) to 100 nM insulin, with untreated solvent control cells (blanks). The central role of hepatic insulin resistance in pandemic metabolic diseases urges investigation of the underlying mechanisms of its developme...

ORGANISM(S): Rattus norvegicus

2012-06-17 | E-GEOD-35697 | biostudies-arrayexpress

Transcription profiling of human hepatoma cells treated with 5-aza-dC, Trichostatin A, both, or control to elucidate the response to inhibition of DNA methylation and histone deacetylation

Expression profiling the response to inhibition of DNA methylation and histone deacetylation. Comparison of expression in HepG2 cells treated with 5-aza-dC, Trichostatin A, both, or none (control) to change methylation and acetylation status. Backgroubd: DNA methylation and histone deacetylation ar...

ORGANISM(S): Homo sapiens

2007-10-27 | E-GEOD-5230 | biostudies-arrayexpress

Expression data of GTSE1-knockdown hepatoma cell line Bel-7404

PRJNA533804 | ENA

Transcriptomic sterol response in the HepG2 human hepatoma cell line

PRJNA788285 | ENA

Human Hepatocyte Proteome - In-depth quantitative analysis and comparison of the human hepatocyte and hepatoma cell line HepG2 proteomes

ORGANISM(S): Homo sapiens (Human)

2016-01-26 | PXD001874 | Pride

Human hepatocyte

Genome-wide analysis of berberine chloride-responsive gene expression in HepG2 liver cell line

Berberine, an isoquinoline alkaloid isolated from many medicinal herbs such as Coptis chinensis, has a wide range of pharmacological effects. Here, we used gene expression microarray to analyze gene expression profiles of HepG2 human hepatoma cell line after berberine chloride treatment or 0.08% DM...

ORGANISM(S): Homo sapiens

2013-10-02 | E-GEOD-47786 | biostudies-arrayexpress

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