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MetabolomicsCharacterizing COPD phenotypes with a targeted signaling lipids metabolomics approach

A targeted metabolomics approach reveals distinct metabolic patterns associated with different GOLD stages, KNGF profiles and SYS subtypes in COPD patients, highlighting unique mechanisms and pathways underlying various COPD classification systems.

2025-07-21 | MTBLS11748 | MetaboLights
MetabolomicsGut Bacteroides act in a microbial consortium to cause susceptibility to severe malaria

Malaria, caused by Plasmodium species, remains a significant cause of morbidity and mortality globally. Gut bacteria can influence the severity of malaria, but the contribution of specific bacteria to the risk of severe malaria is unknown. Here, multiomics approaches demonstrate specific...

2023-09-13 | MTBLS3449 | MetaboLights
UnknownImplementation of a unilateral hip flexion exosuit to aid paretic limb advancement during inpatient gait retraining for individuals post-stroke: a feasibility study.
Not available
S-EPMC11256417 | biostudies-literature
GenomicsHGFAC is a ChREBP Regulated Hepatokine that Enhances Glucose and Lipid Homeostasis
HGFAC is a ChREBP Regulated Hepatokine that Enhances Glucose and Lipid Homeostasis
PRJNA901511 | ENA
UnknownA CD25-biased interleukin-2 for autoimmune therapy engineered via a semi-synthetic organism.
Not available
S-EPMC10966033 | biostudies-literature
TranscriptomicsTranscriptome analysis of 103 RILs of a B73 x H99 RIL population
The RIL population used in this study is derived from a cross between parental lines B73 and H99, followed by 12 generations of self-pollination. In total 142 RILs were generated and 223 markers were used for mapping these RILs (Marino et al. (2009) Mol Genet Genomics, 281:163-179). The transcriptom...
ORGANISM(S): Zea mays 
2015-07-24 | E-MTAB-3758 | biostudies-arrayexpress
MetabolomicsDisease phenotype prediction in multiple sclerosis

Progressive multiple sclerosis (PMS) is currently diagnosed retrospectively. Here, we work towards a set of biomarkers that could assist in early diagnosis of PMS. A selection of cerebrospinal fluid metabolites (n=15) was shown to differentiate between PMS and its preceding phenotype in an indepe...

2023-05-31 | MTBLS1464 | MetaboLights
MetabolomicsAlterations in the tyrosine and phenylalanine pathways revealed by biochemical profiling in cerebrospinal fluid of Huntington’s disease subjects
Huntington's disease (HD) is a severe neurological disease leading to psychiatric symptoms, motor impairment and cognitive decline. The disease is caused by a CAG expansion in the huntingtin (HTT) gene, but how this translates into the clinical phenotype of HD remains elusive. Using liquid chromatog...
2019-06-21 | MTBLS749 | MetaboLights
UnknownNSC348884 cytotoxicity is not mediated by inhibition of nucleophosmin oligomerization.
Not available
S-EPMC7806638 | biostudies-literature
ProteomicsTriple Null, a soybean bred to lack major seed allergen P34 and bioactive lectin and kunitz trypsin inhibitor
Seeds, including soybean (Glycine max), contain bioactive proteins with anti-nutritional and immunological properties that affect metabolism and assimilation of seed derived nutrients and as allergens that can induce escalating adverse immune responses. The presence of anti-nutritional proteins requ...
ORGANISM(S): Glycine max 
2022-02-23 | PXD000967 | Pride
Null Seed Soybean Allergen 
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