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TranscriptomicsAbundant Quantitative Trait Loci for CpG Methylation and Expression Across Human Brain Tissues
A fundamental challenge in the post-genome era is to understand and annotate the consequences of genetic variation, particularly within the context of human tissues. We describe a set of integrated experiments designed to investigate the effects of common genetic variability on DNA methylation, mRNA...
ORGANISM(S): Homo sapiens 
2010-04-20 | E-GEOD-15745 | biostudies-arrayexpress
UnknownQTL mapping of human retina DNA methylation identifies 87 gene-epigenome interactions in age-related macular degeneration.
Not available
S-EPMC10312909 | biostudies-literature
UnknownQTL mapping of human retina DNA methylation identifies 87 gene-epigenome interactions in age-related macular degeneration.
Not available
S-EPMC10912779 | biostudies-literature
UnknownAssociation of IFN-γ +874 A/T SNP and hypermethylation of the -53 CpG site with tuberculosis susceptibility.
Not available
S-EPMC9892940 | biostudies-literature
UnknownThe Nuclear Receptor Nurr1 Modulates the Expression and Activity of PPARγ in Human Pro-Inflammatory Macrophages.
Not available
S-EPMC12550473 | biostudies-literature
TranscriptomicsTumor exosome integrins determine organotropic metastasis
Stephen Paget first proposed, in 1889, that organ distribution of metastases is a non-random event, yet metastatic organotropism remains one of the greatest mysteries in cancer biology. Here, we demonstrate that exosomes released by lung-, liver- and brain-tropic tumor cells fuse preferentially with...
ORGANISM(S): Homo sapiens 
2015-06-17 | E-GEOD-68919 | biostudies-arrayexpress
UnknownImaging-genetics of sex differences in ASD: distinct effects of OXTR variants on brain connectivity.
Not available
S-EPMC7054353 | biostudies-literature
UnknownCross-phenotype analysis of Immunochip data identifies <i>KDM4C</i> as a relevant <i>locus</i> for the development of systemic vasculitis.
Not available
S-EPMC5849568 | biostudies-literature
GenomicsNINDS-Genome-Wide Genotyping in Parkinson's Disease: First Stage Analysis and Public Release of Data

Epidemiological studies have estimated a cumulative prevalence of PD of greater than 1 per thousand. When prevalence is limited to senior populations, this proportion increases nearly 10-fold. The estimated genetic risk ratio for PD is approximately 1.7 (70% increased risk for PD if a sibling...

phs000089.v3.p2 | EGA
UnknownPancreatic cancer exosomes initiate pre-metastatic niche formation in the liver.
Not available
S-EPMC5769922 | biostudies-literature
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