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TranscriptomicsAnalysis of global gene expression of a human T-ALL cell lines, comparing GATA3low ETP-ALL (i.e. PER-117) and "typical" T-ALL
Cell lines representing human T-ALL were analyzed to compare GATA3low ETP-ALL (i.e. PER-117) with "typical" T-ALL. Moreover, changes in global gene expression were assessed comparing GATA3low ETP-ALL (i.e. PER-117) and GATA3high ETP-ALL (i.e. Loucy) upon treatment with Decitabine, a hypome...
ORGANISM(S): Homo sapiens 
2016-02-26 | E-GEOD-78166 | biostudies-arrayexpress
TranscriptomicsMicroarray analysis of the migrating human CD4+ T cell population from the spleen of humanized mice in response to treatment with Teplizumab or hIg
In order to identify genes expressed by cells that leave the spleen, the spleens were harvested from untreated reconstituted humanized mice (N=4) and a single cell suspension was prepared . The cultures were treated with either teplizumab (anti human CD3 hOKT3g1(Ala-Ala)) or hIg for 18 hrs in vitro...
ORGANISM(S): Homo sapiens 
2012-02-27 | E-GEOD-34163 | biostudies-arrayexpress
UnknownLow number of intrafollicular T cells may predict favourable response to rituximab-based immuno-chemotherapy in advanced follicular lymphoma: a secondary analysis of a randomized clinical trial.
Not available
S-EPMC6658576 | biostudies-literature
UnknownPD-1 blockade does not improve efficacy of EpCAM-directed CAR T-cell in lung cancer brain metastasis.
Not available
S-EPMC11447167 | biostudies-literature
TranscriptomicsSilencing of GATA3 defines a novel stem cell like subgroup of ETP-ALL
Genome wide expression profiling was used to detect cases of adult T-ALL lacking GATA3 expression. GATA3low T-ALL exhibited enrichment of myeloid/lymphoid progenitor (MLP) and granulocyte/monocyte progenitor (GMP) genes, while T-cell specific signatures were downregulated. Among upregulated genes FL...
ORGANISM(S): Homo sapiens 
2016-02-26 | E-GEOD-78132 | biostudies-arrayexpress
UnknownTargeting Inflammatory T Helper Cells via Retinoic Acid-Related Orphan Receptor Gamma t Is Ineffective to Prevent Allo-Response-Driven Colitis.
Not available
S-EPMC5992389 | biostudies-literature
UnknownSynergistic targeting of breast cancer stem-like cells by human γδ T cells and CD8+ T cells.
Not available
S-EPMC5550559 | biostudies-literature
UnknownIdentification and Analysis of Islet Antigen-Specific CD8+ T Cells with T Cell Libraries.
Not available
S-EPMC6449153 | biostudies-literature
UnknownLiver X receptor activation promotes differentiation of regulatory T cells.
Not available
S-EPMC5604992 | biostudies-literature
UnknownStandardizing T-Cell Biomarkers in Type 1 Diabetes: Challenges and Recent Advances.
Not available
S-EPMC6609980 | biostudies-literature
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